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Nina Jeliazkova
Works at IdeaConsult Ltd.
Lives in Sofia,Bulgaria
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Nina Jeliazkova

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 EFSA, “Modern methodologies and tools for human hazard assessment of chemicals 1,” vol. 12, no. 4, pp. 1–87, 2014.

"A generic application of the TTC includes to the categorisation of chemicals based on their level of concern for oral systemic toxicity (Cramer classification scheme), and to the prediction of the potential for genotoxicity using in silico tools. These in silico tools include the widely used software tool Toxtree, which is freely available at http://ihcp.jrc.ec.europa.eu/our_labs/predictive_toxicology/qsar_tools/toxtree and http://toxtree.sourceforge.net/ "

http://www.efsa.europa.eu/fr/efsajournal/pub/3638.htm
doi:10.2903/j.efsa.2014.3638
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Roger and I responded to the controversy around the journal that banned p-values today in Nature. A piece like this requires a lot of information packed into very little space but I thought one idea that deserved to be talked about more was the idea of data analysis subcultures. From the paper: ...
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What if a simple photo of your plate was enough to analyze its nutritional content?
Our smartphones can do a lot—compute, pin down our location, sense motion and orientation, send and receive wireless signals, take photographs
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Even if not April 1 joke, if you read the chemometrics journals, you'll see how much trouble it gives to measure properties of mixtures even in a quite controlled environment...
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Craig Venter - DARPA Keynote.

Very interesting 25 minute keynote talk by Craig Venter at a recent DARPA session. Informal and engaging, Venter weaves through the recent history, current status, and future directions of DNA sequencing, genomics, and synthetic biology.

You'll be surprised at the current capabilities of a very few organisations building out the edges of what is possible. Recall Gibson: The future is already here, it's just not evenly distributed yet and project volumes, cost reduction, miniaturisation, maturation, and decentralisation. 

One of a number of highlights includes a working device able to read a specification and print out on demand DNA, RNA, proteins, etc, and which they have tried to wrap in security to prevent "printing" ebola for example. But this device already exists; it's only a matter of when, not if, you'll have a device in your home able to program and synthesise novel living systems, vaccines, and biomolecules. 

#syntheticbiology   #craigventer   #genomics  
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Wow, synthetic phage therapy is a convincing concept. Thanks for that.
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D. P. Elder, A. White, J. Harvey, A. Teasdale, R. V. Williams, and E. Covey-Crump, “Mutagenic Impurities: Precompetitive/Competitive Collaborative and Data Sharing Initiatives,” Org. Process Res. Dev.,  2015. http://pubs.acs.org/doi/pdf/10.1021/acs.oprd.5b00128

"The overall performance of Toxtree, Leadscope Expert Alert System, and Sarah Nexus compare favorably to the most widely-used commercial model systems tested previously with the same data sets, and provide sufficient transparency and interpretability for the qualification of pharmaceutical impurities under ICH M77." 

Strangely, this sentence is the only place in the paper ever mentioning Toxtree, while the performance of the other systems is discussed at length.
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"Games are to AI researchers what fruit flies are to biology — a stripped-back system in which to test theories"

http://www.nature.com/news/game-playing-software-holds-lessons-for-neuroscience-1.16979
DeepMind computer provides new way to investigate how the brain works.
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Of Containers, Dockers, Rockets, and Daemons
This is an interesting post about +Docker, #rocket , #freebsd  and #zfs .  
I don’t feel up to porting whole of Rocket to FreeBSD’s ports right now (but who knows? The codebase looks simple and straightforward), but as I am trying to quickly whip up something container-like on top of jails for my own project, I have some already written, well-designed specification I can work with, and some code that I can at least partially reuse.
Thanks +Jochen Breuer for linking to this post in one of your recent comments.
I have started using Docker soon after it showed up. I've been running dockerized services in production since well before 1.0. I am still using it quite extensively and recommend it to people. I have also recently decided to run my next project on FreeBSD. I've been playing with this system for ...
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Have her in circles
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Nina Nikolova
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"O traveler, there is no path. Paths are made by walking."
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Sofia,Bulgaria
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Burgas, Bulgaria - St. Petersburg, Russia - Brussels, Belgium
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