Scrapping Excessive Neural Connections Helps Build New Connections

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The formation and refinement of neural networks is known to be often an activity-dependent process, but mechanisms and nature of activity are not yet clearly understood. During neuronal circuit formation, afferent axons often make multiple, exuberant, or aberrant connections, which are later eliminated, sometimes in an activity-dependent manner. Such examples are widely seen throughout the central and peripheral nervous systems.

The research is in European Journal of Neuroscience. (full access paywall)

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