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Microglia Cells Renew Themselves Quicker Than First Thought

"Microglia are constantly scanning the brain to find and fix issues - you could call them the housekeepers of the brain," said Dr Diego Gomez-Nicola, of the University of Southampton, who supervised the study. "We previously thought that microglia would renew themselves so slowly that a whole lifetime would not suffice to renew the whole population. But now we can talk about up to six renewal cycles in a lifetime. We now need to reinterpret how they interact and regulate the function of other brain cells to understand their full potential."

The research is in Cell Reports. (full open access)
Summary: The turn over of microglia cells is at least ten times faster than previously predicted, allowing for entire renewal of microglia a number of times during ones lifetime, a new study reports.
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