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This article – by one of the discoverers of Mimivirus – argues that the new giant DNA viruses are different from other viruses and that as a result, we neew to create a new brach of microbes. Other virologists are more cautious, suggesting that Mimivirus…
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With the fall in H1N1 “swine flu” influenza cases recently, it has become fashionable for the media to run “What was all the fuss about” stories on the same page as “OMG, it’s going to be bad” stories. The problem with influenza is that it is one of the…
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A half century of structural studies have shown the design principles controlling self-assembly of viral proteins into icosahedral virus capsids. A large repertoire of virus structures, mainly determined using X-ray crystallography and cryo-electron…
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It’s quite remarkable that after so many years of studying prions we still don’t have a good understanding of their pathogenesis – how do they make normal cellular proteins turn evil? This interesting article suggests that it’s not the end stage amyloid…
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Influenza A viruses circulate in various natural hosts, including mammals and birds. Transmission of influenza virus between mammals and birds occurs only rarely, owing to host restriction: an influenza A virus that is adapted to an avian host typically…
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http://www.leicestermercury.co.uk/Person-Doomed-science-save/story-28318859-detail/story.html Recently there were stories in the media about a new superbug that might kill us all. This started with the discovery of bacteria in China which are resistant to…
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Influenza pandemics have been recognized for centuries, but the virus responsible was not isolated until 1933. Influenza virus particles are highly variable in shape. Mostly are spherical or oval and 80-120 nanometres (nm) in diameter, but long…
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Influenza viruses are a major public health threat. Each year, the typical seasonal flu epidemic affects millions of people with sometimes fatal outcomes, especially in high risk groups such as young children and elderly. The sporadic pandemic outbreaks…
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Patients who succumbed to influenza during the 1918 pandemic had severe lung pathology marked by extensive inflammatory infiltrate, indicating a robust immune response in the lung. Similar findings have been reported from H5N1-infected patients, raising…
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It’s often said that the bacteria and other microbes in our body outnumber our own cells by about ten to one. But that’s a myth that should be forgotten according to a new paper – the ratio between resident microbes and human cells is more likely to be…
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When I started my scientific career by working on polio vaccines over 30 years ago, we were already thinking about newer, safer vaccines. Although polio eradication remains tantalizingly out of reach, we are close enough now to think in detail about what…
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The last few years have seen an increased interest in immunotherapy in the treatment of malignant disease. In particular, there has been significant enthusiasm for oncolytic virotherapy, with a large amount of pre-clinical data showing promise in animal…
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Have them in circles
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soon valley's profile photo
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MicrobiologyBytes brings you the latest news about microbiology in a form that's easy to understand.