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Highlights from The People's Medicine Community. Share your drug related questions and stories anonymously in our free community. No registration is required.
Highlights from The People's Medicine Community. Share your drug related questions and stories anonymously in our free community. No registration is required.

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Is #harvoni a viable treatment option for hepatitis C? Community Discussion: “Now 9 months post, and my life is ruined. I really don't know what to do. I had the lump on my scalp removed (benign), but I get painful bumps on my scalp that last for weeks for no reason. I am getting ready to have surgery to see if that can correct some of the pain in my back and legs, have been undergoing spinal inj's. for 2 months now. But they cannot explain the edema and blackening/bruising of my lower legs. My hematocrit is high, my creatinine is high, my calcium is high, my BUN is high. My blood pressure soars for no reason, (176/128), my vision sucks, it is like having a grey curtain that moves back and forth across your face. My heart feels like it is having to work triple time. Food has no taste. I can't remember anything, I find myself fuguing out for hours. I'm not here anymore. I am not depressed or suicidal. I simply have no survival mode. 2 seconds away from losing my job and I have no ability to focus long enough to figure out what is going on. I live by myself. I have no one here, I moved here for the job and the only people I know are the people I work with. I just can't seem to figure out what is happening to me.“

Source: https://www.medschat.com/Discuss/long-term-side-effects-of-harvoni-307282.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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Does anyone else take #contrave for weight loss? Community Discussion: “I'm on my second round of contrave. When I first tried it, it took until week 4 to start working. I remain on it for 6 months and lost about 18 pounds. My blood pressure starting going up and up and then it wasn't controlling my appetite. I gained back about 8 lbs so because it wasn't working and it was causing high blood pressure I stopped for 3 months. I went back on Phentermine for 3 those 3 months. I maintained the weight and the blood pressure went right back to normal again. I went back on contrave and now I'm on week 4. Still not seeing a decrease in my appetite yet. I'm so hoping it will work like it did before. My blood pressure is going up again. I take 2 pills when I get up around 9-10am and then again about 10-11pm. Just curious about the time the successful people are taking theirs? I called the company and they said I was administering it correctly. I'm really hoping it will start working again.”

Source: https://www.medschat.com/Discuss/Contrave-and-appetite-control-290475.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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#Opioid_Replacement_Therapy Community Discussion: “I've been prescribed buprenorphine for long acting pain management as well as Medication Assisted Treatment for 3 years in Palm Beach county Florida. I've always filled my prescriptions at Publix Pharmacy. I have 1 and 1/2 weeks left before I can refill. But Publix, all of them are saying their distributors are all out of stock. I've asked my pharmacist if this is normal, I was told no. I asked if he could find out quickly if this was permanent and he said he'd call both distributors to find out. Now, a week later, he's being evasive and says he hasn't gotten an answer. If I run out I could relapse, and I've been clean and sober for more than 8 years. I'm scared to death. Does anyone have any answers?“

Source: https://www.medschat.com/Discuss/Buprenorphine-Availability-In-Florida-334401.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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#Pain_Management From our forums: “How long would the average person expect to get by taking 20mg Oxycodone 2x a day, before the body builds up a resistance and the MG has to be raised? I know lots of people are taking 60mg at a time doses of Oxycodone and I REALLY hope for that not to happen to me! So, how long can I expect to get by on 20mg 2x a day? I can not sleep taking Oxycodone, so I can't take 10mg 4 times a day. I tried and stayed up all night 2 nights in a row. I'm almost 70. I have been taking Oxycodone for over 15 years, but, 15 years ago, I just took 10mg on days that work left me in agonizing pain for a few days after. I have had arthritis in my spine since 1991. That was when it was first seen, as I got a cat scan, Xray, or MEI - I don't recall and the doctor showed me it on the monitor. I was in the hospital, from falling of a a 1/2 story roof and landing on a wood deck. From then on, the pain increased. Then a car accident in around 2010 put me in the hospital and they said I had herniated and bulging discs - I don't recall them specifying how many? Anyway, then more and more often I needed to take the Oxycodone for constant pain, that would get worse, after each time I pressure washed or cleaned a roof. Up to this point, strictly out of fear of addiction, I never-ever-took it more than 3 days a week and usually 2-but steadily, every week, by 2013. In 2014 I had 2 heart attacks [don't know that they count for anything] and also in 2014 I was in a bad car accident.

Someone ran a red light and flipped my van over. Again, hospital said herniated discs, but this time, they said 2. One in my lower neck and 1 in my lower back and quite a bit of arthritis[degenerative] Then in 2015 another heart attack and another car accident. Again, someone ran a red light and destroyed my big GMC truck and the 6x10' trailer, with 2 tanks = 150 gallons total + 2 big pressure washing machines and about 600' of 6000psi pressure washing hose = heavy stuff! and another 250' of 3/4" garden hose, plus other equipment = a very heavy trailer! The SUV that hit my tryck passenger door, knocked me into a jack knife and I hit a new style 1' tall curb, went over that, crossed a sidewalk and was stopped by another cement curbing in town, that separated the bushes from the walk. I was knocked unconscious and the hospital said 3 herniated discs, plural bulging discs [don't recall how many?] and arthritis in my entire spine. After that 10mg would not touch the pain, so I started on 20mg, but still, out of fear of addiction, never took it more than 3 days a week - EVER, but I definitely took it 3 days every week. 1 year and a few days ago, my family doctor said he was no longer prescribing any narcotic pain meds and sent me to a pain doctor. He gives me 120 10mg oxycodone a month and I have taken 20mg 2 x a day ever since and just sit in a chair with ice packs after each new increase in pain, due to some sort of work and then switch to wet hot packs - each for 20 minutes to a half hour at a time 4 or 5 times a day and it helps some. I have noticed a reduction in how well the 20mg has been working lately. It seems it used to reduce my pain level by around 50% and now, closer to 33% or so. I don't want to take more, if I can avoid it, but I'm unsure of how to live with the pain and have any kind of life, to speak of?

I have too many friends and acquaintances at work, who had bad experiences with surgeries. Some say it helped, but then some of them say, a year later the pain returned and they needed another surgery! But, most say "DON'T GET BACK OR NECK SURGERY! YOU'L BE SORRY!" I have an unnatural fear of surgeries anyway, so that's out, unless absolutely unavoidable! Any ideas or advice? Medical marijuana is in Florida now, but from what I hear, it's complicated to get a card for it and I don't know if it would work anyway? What do you all think? Also, back to my original concern too - How long does it ordinarily take for a person's body to become resistant to a 20mg dose, so that it must be increased? I know every individual will be different, but there must be some norm? I ask, because, as I said, I feel like it's not working as well as it used to? PS: I was actually on Percocet 10/325 up until 2 months ago. I read about liver damage from Tylenol and asked my doctor if I could just get Oxycodone alone and he had no problem with that. Well, the site said to give a detailed description and I tried! LOL. I will appreciate any suggestions. I wondered about: would it be reasonable, to switch to a different opioid? Like Hydromorphone etc etc etc? I forgot to mention! I told my doctor about this and 2 months ago, he added 15mg Morphine sulphate 2X a day, but I got bad reactions and stopped it after about 10 days. I told him and he just said "Okay"?”

Source: https://www.medschat.com/Discuss/How-long-on-average-to-build-a-resistance-to-Oxycodone-20mg-2x-a-day-334408.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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#Remicade Community Discussion: “I was diagnosed with rheumatoid arthritis and ankylosis spondylitis in 1998. By 2000 I was so crippled I could barely walk. Anti-inflammatory meds were dropping my weight and not working. Methotrexate gave me heart murmurs and made me pass out. Remicade was new, not much was known about it, i figured it was worth a try. After my 1st infusion I felt better, I went into remission but stayed on every 8 weeks. Amazing for 10-15 years. At 1 point I had an insurance change, switched doctors. She took me off remicade because I was in remission, also she didn't like the drug and thought it was much too inconvenient to sit through infusions. She felt I didn't need it. I didn't mind sitting through infusions... Within a month I was flaring, tried enbrel, almost died from methotrexate, eventually landed on humira. Great drug, I could tell the disease was active, but I could deal with it. About 5 years into humira I started to develop horrible psoriasis. Tanning kept it at bay, so I went on for another year. Then I started getting flu-like feelings the second week of humira shots. I was receiving shots biweekly. I took myself off humira. Not long after I was in the hospital for shoulder pain, doc thought possibly a clot, ct scan showed nothing except spots in my lungs. After scans and biopsy of the lung it was ruled I have rheumatoid lung nodules. I was put on prednisone, it worked great, shrunk nodules.

My rheumatologist kept me on 10mg prednisone and also another anti-inflammatory. Over a year went past, I couldn't take the pain and sick feeling anymore, so I switched rheumatologists. My new doc is 3 hours away, but he seems great. He immediately started me back on remicade, the next day my psoriasis was almost gone. I had side effects like headache and anxiety, flush, elevated heart, but nothing I wouldn't take over the suffering I had before. When I was on remicade in the 2000s I was never pre-medicated, never had side effects, nothing. Simply felt great! April 2017 is when I started back on remicade, April, May, June were great, then I started to notice the infusions were getting less effective, psoriasis was coming back, but worse of all the dreaded flu-like feeling. Flush, headache, short of breath, nausea, dizzy, fatigue, fatigue, fatigue!! Constant feeling of fever, but never have one. Stiff, mostly neck and spine, it hurts so bad! I still to this day have this, my doc says it's from inflammation and I should start leflunomide to help the remicade from building antibodies. Due to the bad experience from methotrexate in the past I'm extremely hesitant to take it. My doc wanted to boost my remicade few months ago, insurance said no. I now have a new insurance, my doc says upping my dose is a possibility now that I have new insurance. He still wants me to start leflunomide. My girlfriend and I are trying to conceive so the doc says to hold off on the leflunomide for now. I can never get enough time with my doc, he's good just seems to rush me. I bring up antibody evaluations and he tells me my insurance prob won't cover it and he feels I'm not building antibodies, I just need a maintenance drug.

If I'm not building antibodies then why is it becoming less and less effective? I get an infusion now and feel good for 2 weeks, then boom. Tired, flush, nausea, short of breath, headache, dizzy, tired, weak, my voice gets hoarse. My back and neck hurt sooo bad. I can feel the inflammation, it's not nearly as bad as when I'm on no meds, but still bad. I will go through this for a few days to a week, then it goes away. Even my inflammation will get better. I will enjoy life, feel great, but the sickness comes back. Sometimes a week or 2 weeks. I'm down to 7.5 prednisone, I feel it contributes to my problems. I can't get off the stuff because my psoriasis is sooo bad. I feel like my body is fighting with remicade, work, not work. I don't want to start leflunomide if I'm building antibodies to remicade, seems like a waste. My biggest concern is the getting sick all the time. Why? I never use too, it's certainly just been a couple years. During the summer I fight through work, sick feeling, tired, stiff, but still work. I enjoy being physically active, riding snowmobiles, driving dirt track racecars. It's hard to do these things if i'm constantly feeling so sick. It adds to my reasons for not starting leflunomide, if I already feel sick, adding it can't help. My doc says lefludomine is much better than methotrexate safety wise, and I should be ok on it. Should be... I'm waiting for the infusion where I flop from a reaction. I don't want that. I need help with this disease before it kills me!”

Source: https://www.medschat.com/Discuss/Remicade-antibodies-334342.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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What steps are other patients taking to wean off #Propranolol? Community Discussion: “I have taken Propranolol for over twenty years for essential tremors. The dose has been up and down over the years, 80mg has been the most recent one two times a day. This doesn't seem to help much with my tremors. I have to work. I am now 77 years old and cannot write or speak clearly, which I must use both on the job. My heart has stopped three times and have had to be brought back, that is why the up and down doses. A week ago was the last time for my heart to stop; my step son gave me CPR and brought me back, I was taken to Er, no heart checked except for the ekg and was sent home to see my primary physician. She was disturbed that they have never checked my neurological condition or heart over the years so that is what she is starting to do now. I am off of the Propranolol now as this she believes lowers my blood pressure and stops my heart. It has been now a week since I have taken a pill, my tremors are back big time, so we are now starting me on the CBD and that has helped some, but too soon to tell what it will do for the essential tremors. I have a family history of this condition, my mother had only the head shaking, grandmother was both head and hands which I have. It is embarrassing to try to go out to eat, have to have my head in my plate to reach my mouth at times with the shaking so hard. I have had no strange side-effect by the sudden stopping of the drug. I was told not to stop too quickly, but I did and started the CBD. You are welcome to write me back.”

Source: https://www.medschat.com/Discuss/coming-off-propranolol-160031.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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What are the long-term effects of #Amitriptyline? Community Discussion: "I have read extensively about this drug, and I have had terrible withdrawal symptoms, including severe bladder urgency (I had never experienced before). It feels very similar to a bladder infection. From online research, I have found that bladder, stomach and GI spasms are a common experience during withdrawal. This drug works to relax smooth muscles, which is why it is often prescribed for bladder and GI issues. When you withdrawal from the drug, those same muscles can begin not only working again, but having unnaturally strong, or too frequent spasms causing urgency, cramps, and stomach and back pain.

I was prescribed 25-50 mg. of Amitriptyline for nerve pain in my back just 5 months ago. The Amitriptyline almost controls the nerve pain, unless I do a lot of work. Concerned with the possible long term damage to my teeth, and digestive system due to the side effects I've experienced: severe constipation, serious dry mouth, serious stomach pain, I've been trying to stop taking Amitriptyline. I've also gained 10 pounds in this short time after being the same weight for over 20 years. Weight gain is listed as the number one reason people want off this drug.

I reduced the prescribed med, supplementing with naproxen (Aleve), to half a 25 mg tablet, then 1/4 of a 25 mg tablet over a 1 1/2 month period. Then I stopped completely for three nights. I used store brand Benadryl to help me sleep; sleeping better is one side effect of Amitriptyline that I'll miss. For three days I felt so much better overall except for dealing with my nerve pain. My healthy bowel function returned, I had more alertness and energy, my mood was much lighter. Then on the fourth day without Amitriptyline, I woke up crying and moaning in pain with severe cramping of my colon, causing severe stomach and back pain. Also, the feeling of a bladder infection with the severe, constant urgency even after I'd just urinated. The only reason I did not go to the E.R. is because I had already read of many people experiencing the same withdrawal symptoms. After a few days of this I went back on half a 25 mg. tablet and the pain and urgency stopped completely within two days. Still I went to the doctor for an exam just to make sure I didn't have a urinary tract infection, or something worse. The U/A was clear, and the exam didn't uncover anything unusual. Since being back on Amitriptyline, none of the above withdrawal symptoms have returned.

Many people have successfully withdrawn from Amitriptyline without too many bad effects, but many people will experience negative health issues that are worse than the problem we were prescribed medicine for in the first place. You can find their stories all over the internet. Most people say the withdrawal symptoms eventually disappear after a very slow, many months long, very gradual withdrawal. Unfortunately, I've seen several patients whose withdrawal effects have never completely healed. I'm determined to get off these things. Good luck to everyone.“

Source: https://www.medschat.com/Discuss/Effects-of-Long-Term-Amitriptyline-Use-on-the-Heart-210067.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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How would you describe your experience with #Lyrica? Community Discussion: “I was on 300mg Lyrica for four years and decided to come off it this past October. I felt I was like an addict. I got so sick with depression anxiety and panic attacks. Diarrhea for a month. I lost 27 lbs. I was in the ER for dehydration and severe nausea and gagging. I could not look at food nor eat. The family doctor put me on a very low dose of Ativan to help with the anxiety. I finally decided to go to a psychiatrist to help me overcome all this crap. I followed the withdrawal to a tee. I still have to get off 50mg by decreasing to 25mg once a day for a week. Now I know why people take their lives! Who would of thought this drug could do this to a person? I’m still struggling big time, driving is hard and going out isn’t easy either. I just want my life back and Pfizer sued!”

Source: https://www.medschat.com/Discuss/Lyrica-withdrawals-winging-off-173659.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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Has anyone else taken generic #Percocet by Camber Pharmaceuticals? Community Discussion: “I used Walgreens for years all the way up until i had an issue with my prescription for Percocet being filled with Camber pills instead of what i had been getting normally. First, I think the pharmacy should verbally tell you there was a change. I shouldn't get home and go to use my meds for the first time since my refill and have my first reaction be "what the heck are these" then see a green sticker on the side of the bottle stating the size, shape or color may be different but this is the same drug you have been getting. I thought nothing of it at first. But the Camber pills made me ridiculously sick. I took the 5/325 pills and i suffered intense nausea, vomited up a fair few of the pills. By the way, when you start puking smurf blue there's a problem. I had migraines. I called the pharmacy only to be told I accepted the medication. Once it goes over the counter there is nothing they can do. They also informed me that the switch to Camber was permanent. My dr called to see if they would order the Actavis pills since the Camber ones were making me sick, nope. I went to the Camber site and was shocked to see under the allergen info "dye free" when the ingredients clearly listed dyes (blue for my dosage). I had the most ridiculously hard time getting the pills replaced. Nobody would take back the Camber pills. Everywhere I went just pointed me to their drop box. But my dr would not write a new script without proof i disposed of the pills I had. I couldn't give them to the dr's office. They couldn't legally handle them.

They told me to surrender them to the police department, who also couldn't handle them. I was told to just put them in the drop box. In the meantime i kept puking blue and if i didn't get sick I was nauseous, had the worst headaches. I complained to Camber, mostly about their allergen info being incorrect. They emailed me back with a link basically calling me a liar. They had flxed it, but I had taken a screenshot. So nice try Camber. I reported them to the FDA with copies of the screenshots. Turns out I have an allergy to the blue dye. I was eventually able to get rid of the Camber pills and get a new script from a local pharmacy the was able to verify what they use and it is now on my record to not be given any meds with blue dye. But it took weeks to get sorted out. And i was left with the option to take pills that are making me sick or go through withdrawals and suffer in pain. Which is crap. Now i keep getting contacted by reps from Ascent Pharmaceuticals wanting me to fill out their forms. They also tried to claim they never listed the drug as "dye free" -again nice try, i still have the screenshot, which i sent back to them. I also asked them to leave me alone. I switched pharmacies, i will not accept any medication they make, ever. I just had spine surgery and I don't feel like dealing with them. I filed many complaints. They make poison. And now i know Walgreens will carry anything to make money.”

Source: https://www.medschat.com/Discuss/Camber-Pharmaceuticals-Generic-Percocet-332133.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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#Wellbutrin #Patient_Assistance Community Discussion: “I was on the generic version for a few years, and they seemed to be okay. However, I was noticing that depending on the "manufacturer" of generics, either my depression would come back, or I would have a lot of stomach issues (blood in my stool at one point), headaches, nausea. I have tried Anchen, PAR, Global Pharmacy, another one that I can't think of the name right now. Once I found Direct Success and started back on the brand name Wellbutrin, I was back to feeling like myself again. I'm not about to try that again... I know it's around a 4 hour drive to Las Vegas, maybe Arizona is closer. I have around 30 days left of my existing supply, so at least I found this out with enough time to spare. My doctor is supposedly calling the CVS, as they do have limited exceptions (according to my internet search on the law) so my fingers are crossed... Thanks for your reply!”

Source: https://www.medschat.com/Discuss/Wellbutrin-program-discontinued-at-Direct-Success-Pharmacy-311694_s2.htm?utm_source=googleplus&utm_medium=social&utm_campaign=social_media
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