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Mary Mangan
Attended University of Massachusetts Amherst
Lived in Somerville MA
25,357 followers
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Bioinformatics, Genomics
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Previously
Somerville MA
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Tagline
Independent scientist. Spectacularly combustible.
Introduction
I've been fascinated with biology since spending summers at the beach engrossed by the tide pools. This led to degrees in Microbiology, Plant Cell Biology, and eventually a PhD in Cell, Molecular, and Developmental Biology. Moving to computational biology, bioinformatics and genomics as those fields emerged, I find databases are the new tide pools for me. And new waves keep washing interesting things in.... For some publications, you can see my Google Scholar profile
Bragging rights
I defend science from crankery whenever I can. Science blogging at blog.openhelix.com and personalgenomics.us, as well as participating at many other blogs. Oh: and I'm probably more Neandertal than you are.
Education
  • University of Massachusetts Amherst
    Microbiology and Immunology, 1983 - 1988
  • Mount Holyoke College
    Biology, 1988 - 1990
  • University of Rochester
    Cell, Molecular, Developmental Biology, 1990 - 1996
  • The Jackson Laboratory
    Bioinformatics, 1996 - 1998
Basic Information
Gender
Female
Other names
@mem_somerville

Stream

Mary Mangan

General Discussion  - 
 
Hey folk-- +Tamar Haspel asks us to weigh in on this. After I stop laughing, I will. 

#GMO  
“Hey you guys! @robertagreer says GMO opponents have "biology backgrounds" and supporters are "just" journos & economists." Wanna weigh in?”
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+Mary Mangan oh my that was a funny one!
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Mary Mangan

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Nice piece on some #GMO  cattle. They can avoid the painful process of de-horning the bovines with just a little bit of gene editing. Unless anti-GMO folks want to keep this procedure going. That would be painful.
Scott Fahrenkrug thinks he can tweak farm animals' genes to make them happier and healthier.
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sory.. the land of luddites had nothing to be proud of.. Right now they are waging a war in the middle east to make way for the woobie to come back..

Nice try and thanks for the idiot attempt at patronisation.
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Mary Mangan

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That's an incredibly deceptive clip. You don't say anywhere that this is a computational model and you haven't bothered to actually measure these in actual soy samples. You also don't note that your software isn't available for people to test and see how accurate your hypothetical values are. 

But I'm sure you are now running to your email to answer +Kevin Folta's offer to test these in real samples. He's eager for you come and do the work. http://kfolta.blogspot.com/2015/07/gmo-formaldehyde-challenge.html

Hmm. Other people say they aren't seeing my comment publicly on this video. I'm going to try a G+ share instead, in case they are being deleted. This is a copy of what I said over there.

#GMO  
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Dave Pentecost's profile photoRajini Rao's profile photoMary Mangan's profile photoSebastian Larsen's profile photo
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+Dave Pentecost thanks, that's both hilarious and frightening. But not at all surprising. It does seem that the worst kind of liars are attracted to the anti-gmo move!ent, like the homeopaths funding that guy Seralini...
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Mary Mangan

commented on a video on YouTube.
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Ooh--when talking about organic "sprouts", I thought for sure you'd bring up the contaminated (er, unclean) organic sprouts that killed all those people. And maybe contrast that with the complete lack of so much as a sneeze from GMOs. 

That said, I don't see it as a "dirt" aversion so much. I think it's yearning for simpler stuff that they can understand. So many people don't understand the benefits of tech for farmers because so few people farm now. I think people have a sepia-toned image of the past, despite the fact that hunger, famine, and food poisoning due to lack of storage technology used to really problematic. In this way I think it's a lot like the vaccine situation. Our success at solving a lot of these things makes people think the past was better. It wasn't.
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I've made something close to that statement multiple times, but not so well as +Mary Mangan​, who is wise.
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Mary Mangan
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Bioinformatics  - 
 
This week's Tip of the Week is out of the recent NAR Web Server issue. A new tool for better looking pathway diagrams, but that still retains their computational usability. Check out PathWhiz.
"Pathway diagrams are the road maps of biology." This is how the folks from PathWhiz begin their recent paper. I came across it in the Nucleic Acids Research
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Mary Mangan

SMH - shakin' my head  - 
 
So I don't actually give a shit about Chipotle's stock price. Or Monsanto's stock price. I don't hold either.

But imagine if this earnings report had gone the other way--that people were flocking to the GMO-free burritos. Yeah.

In the earnings call, they said that the increase in sales was due to increased prices, not because new people were coming in and they were selling more food. In fact, store visits decreased.

Chipotle may bite me.

http://finance.yahoo.com/news/chipotle-investors-not-weak-comparable-205109384.html
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+Mary Mangan well, they sure ain't ever getting any business from me, and I make sure to tell anyone who asks why.
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Mary Mangan

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I'm in. 

#TheNew10   #Barbara10  
3 reason why Nobel Prize winning, American scientist Barbara McClintock should be the woman selected for the new $10 bill #TheNew10 #Barbara10
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Mary Mangan

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I didn't know #signsunday was a thing. But I was looking through some old photos today and this one made me laugh.

It speaks to me. 
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Did not know #signsunday  was a thing. Must dig up my waffle warning.
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Mary Mangan

commented on a video on YouTube.
Shared publicly  - 
 
That's an incredibly deceptive clip. You don't say anywhere that this is a computational model and you haven't bothered to actually measure these in actual soy samples. You also don't note that your software isn't available for people to test and see how accurate your hypothetical values are. 

But I'm sure you are now running to your email to answer +Kevin Folta's offer to test these in real samples. He's eager for you come and do the work. http://kfolta.blogspot.com/2015/07/gmo-formaldehyde-challenge.html
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What I mean is that I am not seeing that comment on YouTube. It makes me wonder if you posted it there and it got removed?
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Mary Mangan

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Finally, someone explains where and how Taleb goes awry with the wild claims about #GMO  ecocide (not). Adam looks at it from the math perspective.

From the biology perspective, it's always been clear that the whole premise is bogus. But Taleb's fans can't acknowledge this because they can't see past their fat tails. But maybe this will catch their attention. 
 
Nassim Nicholas Taleb saw the financial crisis of 2008 coming. As pundits like Jim Cramer confidently declared that Bear Stearns was a safe …
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Mary Mangan

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+Kevin Folta is offering to do the experiment on the formaldehyde claims that are going around. I'll buy them lunch if they actually get this group into the lab and do it.   #GMO  

Forgot the hashtag: #ShowUporShutUp
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as in individual thought...  yer right on that.
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Mary Mangan

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So, it appears that recent Slate piece on #GMO issues has nudged some people out of their previous misconceptions.

Finally.
Plentiful are the takeaways from Will Saletan’s expertly researched, if a bit viciously anti-activist, barn-burner of piece over at Slate on the various absurdities, lies and distortions in the war...
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Not before time.
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