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Mary Mangan
Attended University of Massachusetts Amherst
Lived in Somerville MA
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Bioinformatics, Genomics
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Previously
Somerville MA
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Tagline
Independent scientist. Spectacularly combustible.
Introduction
I've been fascinated with biology since spending summers at the beach engrossed by the tide pools. This led to degrees in Microbiology, Plant Cell Biology, and eventually a PhD in Cell, Molecular, and Developmental Biology. Moving to computational biology, bioinformatics and genomics as those fields emerged, I find databases are the new tide pools for me. And new waves keep washing interesting things in.... For some publications, you can see my Google Scholar profile
Bragging rights
I defend science from crankery whenever I can. Science blogging at blog.openhelix.com and personalgenomics.us, as well as participating at many other blogs. Oh: and I'm probably more Neandertal than you are.
Education
  • University of Massachusetts Amherst
    Microbiology and Immunology, 1983 - 1988
  • Mount Holyoke College
    Biology, 1988 - 1990
  • University of Rochester
    Cell, Molecular, Developmental Biology, 1990 - 1996
  • The Jackson Laboratory
    Bioinformatics, 1996 - 1998
Basic Information
Gender
Female
Other names
@mem_somerville

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Mary Mangan

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I don't give a shit about stock prices and think they have zero relevance to scientific discussion. But a lot of #GMO haters track Monsanto stock all the time as some kind of metric.

It didn't occur to me to look at #Chipotle stock at all, until I read this piece from Natural Society, via twitter. And then I couldn't stop laughing.
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The Internet is unfortunately packed with constant make-shit-uppers. And humans tend to believe their wishes on their enemies, I guess.
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Mary Mangan

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Communists! ZOMG!

Wait, no, that's the wrong #GMO narrative....
It sees bioengineered seeds as vital to a modern farming system
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A gene, and even the protein it creates, are hardly "foreign" substances, as we consume them all the time.  And the amines, sugars, phosphates, and bases they're broken down to in our bodies are universal in living organisms.
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Mary Mangan

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Well, one scientist is able to stay on topic. Alison Van Eenannaam is awesome. Thierry Vrain is bizarre.

#GMO  
Dr. Thierry Vrain and Dr. Alison Van Eenennaam discuss the science behind genetically engineered crops and the significance of GMO restrictions in more than 60 countries
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It does seem like Thierry Vrain has avoided making the many thoroughly refuted claims he has routinely made in the past. One wonders if this is because he knew he wouldn't be able to get away with it in front of Van Eenennaam.

He did keep making very poorly substantiated (if at all) claims about glyphosate. Even his statements about the mode of action of glyphosate are incorrect and this is information known for decades. Glyphosate does not work by chelating metal ions.  You can rescue in vitro systems from the effect of glyphosate with tyrosine and phenylalanine. You cannot rescue them with excess divalent metal cations. I suspect that, stoichiometrically, it doesn't even make sense because there should be way too many available divalent cations around in plant tissue for the molecule to chelate enough of them to make a dent under normal agricultural application rates.
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Mary Mangan

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Wow. Francis Collins is writing at Vox.
The director of the National Institutes of Health explains the importance of scientific research.
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+Mary Mangan times have changed and now industry jobs are where it's at for many science sectors. The problem is that training hasn't caught up with the needs of industry.
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Mary Mangan
moderator

Clinical Genomics  - 
 
This may upset some apple carts.
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Good essay. Software companies can't have it both ways. If the companies want to provide individual diagnostics and recommend therapies, they have to show how the systems work.
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Mary Mangan

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The real villain in Shelley’s story is neither Dr Frankenstein nor his creation – it is the intolerant, torch-wielding villagers.

#GMO  
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«Take the myth of Frankenstein. As Krauthammer, Lewis, and Davis tell it, genetically modified organisms are dangerous»

The pedant in me has trouble with this. From what I've read (I haven't actually read Wheat Belly --but I think I've read articles by him and by that other moron who peddles gluten fear for all), I am guessing that Davis didn't literally mean genetically engineered in his silly book cashing in on gluten phobia when referring to wheat as “frankenwheat” but I know that when many read the above will think we have genetically engineered wheat on the market.
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In her circles
2,416 people
Have her in circles
24,140 people
Çiçekçi Antalya's profile photo
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Corry Andrews's profile photo
Vivek Aanand Ganesan's profile photo
donshua robinson's profile photo
Braun Harald's profile photo
Randy Griffin's profile photo
‫ايهاب الدوري‬‎'s profile photo
Little Progress's profile photo

Mary Mangan

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Hey #Boston folks--reminder before you check out for a couple of days: Monday night--learn stuff! Harvard Square. Hong Kong. Risk Perception.
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Mary Mangan

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This is a fascinating take from an unusual perspective. A guy from an ad agency speaks about the role of ad makers in propagating bad science. Not a side you usually hear from.

#GMO  
Brands peddling pseudo sciences can mean some nasty headaches for agencies they hire says Holler's Mike Hill.
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That makes sense. 
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Mary Mangan

commented on a video on YouTube.
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BAM! Well, that was the best $5 I ever spent on Patreon. OK, it was the first $5 I ever spent. But it won't be the last.
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Mary Mangan

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Heh. I thought the National Geographic "War on Science" cover with the climate deniers, moon-landing fakers, anti-vaxxers, creationists, and GMO haters was remarkable. This is even more direct. 

I just wish they'd fact-checked it. There were never sterile seeds. At least they fixed the 2 other errors already.

#GMO  
The gene-editing CRISPR technology will create crops that can feed us all.
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Mary Mangan

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Hat tip to Ian Street on twitter.
The cover highlights the paper "Restriction Site-Associated DNA Sequencing (RAD-seq) Reveals an Extraordinary Number of Transitions among Gecko Sex-Determining Systems" by Tony Gamble and colleague...
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This is now my wallpaper.
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Mary Mangan

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This is a fascinating twist on the usual label dramas. It will be interesting to see how this plays out.

cc +David Röll #GMO  
A petition aims to make genetic modification acceptable by showing that it’s ubiquitous
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+Mary Mangan I'm sure those german scientists are not completely naive and do not expect to convince GreenPeace and other nuts, but rather they're trying to reach the public, what's something we all should try, isn't it?

+David Röll yes, it was about tobacco, but it was not related to tobacco being drug (otherwise the labelling would change nothing in the first place), but rather about this they label it, thus it cannot be that bad. Of course it depends, who will take the first initiative. Pro-GMOers with some positive labelling or antis with negative warning?
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