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Mary Mangan
Attended University of Massachusetts Amherst
Lived in Somerville MA
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Mary Mangan

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Did you know that koalas have a really serious Chlamydia problem? It sounds odd at first, but it's really damaging their health.

This project is going to take a look at ways that might inform and improve treatment. It's a bargain, kick some cash their way if you want to  help them out.
A research project studying how antibiotics affect the health of koalas | Crowdfunding is a democratic way to support the fundraising needs of your community. Make a contribution today!
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Yeah, I know, I was sort of surprised when that image came up with the link. But it is Katie's project, so that part sort of matters too...
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Mary Mangan

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Heh--this story on the natural #GMO sweet potato includes a funny idea: to edit out the transferred genes with #CRISPR   to make this food ok for organic consumers again!

But that's actually an experiment I'd love to see. It would be fascinating if the potato was any different without the genes. I hope someone does it.
Nature Plants, Published online: 2 June 2015; | doi:10.1038/nplants.2015.77
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I need a scorecard
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Mary Mangan
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Bioinformatics  - 
 
Nice interview with someone who has watched bioinformatics grow into what it is today. Also, he wants a job in Europe next year. Hire him.
We speak with Keith Bradnam about his career to date and his work as one of the premier genomic communicators.
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Mary Mangan

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I read this late last evening and forgot to bring it over. Very amusing take on anti- #GMO and related environmental activism.

NITS = “Nobody Is That Stupid”.
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Mary Mangan

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That #Ebola treatment made with #GMO tobacco is discussed in this short piece. I hope so much that it works in the clinical trials. It would be really great to be able to roll out plant-based drug development to places that could use the flexibility and speed of this strategy.
 
CHARLES ARNTZEN CREATED ZMAPP, THE WORLD’S MOST PROMISING ANTI-EBOLA DRUG, FROM TOBACCO PLANTS
For fighting ebola with tobacco.
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Yeah, the other key feature is that it's not a food crop, so it drives people slightly less insane.
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Mary Mangan

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It says it's been removed.
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Have her in circles
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Mary Mangan
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Bioinformatics  - 
 
Interesting. Graph genomes (or, as I see them in the literature, pan-genome graphics) make the popular science press. And I don't even think most researchers have thought much about this yet.
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This paper also helped me to grasp the concepts of the pan-genome: http://www.ncbi.nlm.nih.gov/pubmed/25565268 Sorry about it being closed access though. It has helpful drawing of the paths from one object to the next that helped to visualize the issues.
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This is a frikken FASCINATING series of near-misses that almost uncovered a fraud--until it eventually was unearthed. It is super-nerdy, but I could barely wait for each paragraph to come. It was like a Dan Brown novel sequence--only sadly real.

Also: good on +David Broockman for hangin' in there, and continuing to tug at the threads.
“What’s the book? There’s no book for this. What do we do?’”
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"My cc is broken." *laughing". I have to remember that one. It is amazing how clueless pathological liars think the rest of us are. 
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Mary Mangan

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Hilarious. But also sad. Creationist makes major fossil find. And denies evolution.

#fossil #evolution #creationism  
That moment when you think the world is 6,000 years old and you dig up a 60 million year old fish.
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+Stevin Abdool Yes, too many do. It's pretty sad. 
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Mary Mangan
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Clinical Genomics  - 
 
This paper is making a splash around my twittersphere. ClinGen, for clinical interpretation of human variations.

There is also a related editorial: http://www.nejm.org/doi/full/10.1056/NEJMe1506276?query=featured_home
Special Report from The New England Journal of Medicine — ClinGen — The Clinical Genome Resource
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Mary Mangan
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Bioinformatics  - 
 
This week's Tip of the Week is a really nice web-based tool for exploring pathways and you can overlay your gene list on them. I found it really easy to use, and handy to link to additional details about the genes.

No panda genes though, only human.
This week's Video Tip of the Week demonstrates PANDA, a tool for generating and examining annotations that are available for a list of genes, and evaluating
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The NYT Archive just tweeted this out. I hadn't read the media coverage of the time--fascinating.

#evolution #scopes  
“John T. Scopes is Indicted in Tennessee for Teaching Evolution, this day in 1925. http://t.co/gsrEbkJPPn”
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After watching a Nova about the Kansas School Board trial, which is an amazing Nova if you can track it down (https://www.youtube.com/watch?v=7HZzGXnYL5I), I was inspired to watch Inherit The Wind. Surprisingly bold and engaging for a courtroom drama about science made in 1960. 
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Have her in circles
24,229 people
Corry Andrews's profile photo
Alan Bond's profile photo
Scott Noble's profile photo
salah ye's profile photo
Justin  Zigbuo's profile photo
Laura Robinson's profile photo
Suzannah Radack's profile photo
Zouhair Mihssan's profile photo
Dushyant Tiwari's profile photo
Work
Occupation
Bioinformatics, Genomics
Places
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Previously
Somerville MA
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Tagline
Independent scientist. Spectacularly combustible.
Introduction
I've been fascinated with biology since spending summers at the beach engrossed by the tide pools. This led to degrees in Microbiology, Plant Cell Biology, and eventually a PhD in Cell, Molecular, and Developmental Biology. Moving to computational biology, bioinformatics and genomics as those fields emerged, I find databases are the new tide pools for me. And new waves keep washing interesting things in.... For some publications, you can see my Google Scholar profile
Bragging rights
I defend science from crankery whenever I can. Science blogging at blog.openhelix.com and personalgenomics.us, as well as participating at many other blogs. Oh: and I'm probably more Neandertal than you are.
Education
  • University of Massachusetts Amherst
    Microbiology and Immunology, 1983 - 1988
  • Mount Holyoke College
    Biology, 1988 - 1990
  • University of Rochester
    Cell, Molecular, Developmental Biology, 1990 - 1996
  • The Jackson Laboratory
    Bioinformatics, 1996 - 1998
Basic Information
Gender
Female
Other names
@mem_somerville