I'm a hardcore ass-to-chair abuser, since I'M working every single day from home cranking out my words and designs. Sounded okay, until I got jaded feelings and a general body fatigue which in return destroyed my productivity. I've written a post about combatting your sitting-in-char danger for +Mark Schaefer
and what you can do to stay fit.
Looking forward to hear your tips -- I'm a noob in that area, so I'm looking forward to learn more 'moves'