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Mark Whiting
Works at Carnegie Mellon University
Attends Carnegie Mellon University
Lives in Pittsburgh, PA, USA
1,396 followers|129,120 views
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448 people
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1,396 people
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Work
Occupation
Ph.D. Candidate
Skills
Answering different questions
Employment
  • Carnegie Mellon University
    PhD Student, 2013 - present
  • KAIST
    Visitin Scholar, 2012 - 2013
  • Adaptive Equipment
    Designer, 2011 - 2012
  • Freelance Consulting
    Innovation Strategy and Design Consulting, 2004 - 2008
Places
Map of the places this user has livedMap of the places this user has livedMap of the places this user has lived
Currently
Pittsburgh, PA, USA
Previously
Daejeon, South Korea - Paris, France - Chapel Hill, NC, USA - Gainesville, FL, USA - Utrecht, Holland - Canberra, ACT, Australia - Melbourne, Victoria, Australia - Hangzhou, Zhejiang, China - Busan, South Korea
Story
Tagline
Computational Design for Bio Applications (I think)
Introduction
I travel a lot and have lived in many places. I love learning and thinking about strange things.

I'm also known for starting TEDxKAIST.
Bragging rights
I have drunk more milk than water.
Education
  • Carnegie Mellon University
    PhD - Mechanical Engineering, 2013 - present
  • KAIST
    MS - Industrial Design, 2009 - 2010
    Studied user creativity as a driving force in design
  • RMIT University
    BDes - Industrial Design, 2004 - 2007
    Studied representations for large scale collaboration and distribution in design work
  • Zhejiang University
    Exchange Student - Industrial Design, 2006 - 2006
    Worked in a design lab and learnt a lot about the industry in China
  • University of Florida
    Non Degree Student - Mathematics & Innovation, 2001 - 2003
    Studied math and patent law
  • Eastside High School - EHS
    International Bacheloriate, 1999 - 2003
    Focused on Math, Chemistry and Robotics.
  • Marist College Canberra
    1998 - 1999
Basic Information
Gender
Male
Looking for
Friends, Networking
Relationship
Married
Other names
Metophile, MarkWhiting, MarkEXW, MEXW

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Mark Whiting

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I'm lucky to have been included in a list of the 99 Google+ pages a PhD candidate should follow.

Thanks Erin, perhaps this will motivate me to use Google+ more.
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Sungwon Peter Choe's profile photo
 
very cool! congrats~
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Mark Whiting

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Totally cool. I wonder if this method works well in most fields. 
 
I'm running my grad course this quarter in a different way.  Instead of homework assignments, we're all writing a book together (https://github.com/williamstein/581f-2013).  When questions or ideas for projects come up in class, the students are assigned to add sections to the text about the discussion, etc.   Most of us are also collaboratively editing everything in a single project on https://cloud.sagemath.com.   At the beginning of every class, we have status reports (just like at Sage Days) in which every reports on exactly what they contributed to the book since we last met -- today everybody had something to say, and it took 15 minutes.    Have you ever tried teaching a grad course this way?
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Ahmed Fasih's profile photo
 
You know who should really adopt this model. The foreign language & literature departments. I'd love to see a new chapter of the Mahabharat or Heike Monogatari come out every semester from every college that teaches Sanskrit or medieval Japanese.
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Mark Whiting
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Introductions  - 
 
I'm also a PhD student at CMU with a background in Design. 

I'm doing this course because I'm interested to see where it will take me. In my current work I'm learning new disciplines (synthetic biology and computational systems design) which seem interesting for the application of design and creativity, and I thought this course might keep my mind in a good place on these matters.
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Mark Whiting

Introduce Yourself  - 
 
I'm Mark Whiting from Australia but currently living in the USA. I'm a PhD student.
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Mark Whiting

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I love this stuff!
 
Smallest rotary motor in biology, the ATP synthase. All the work done in your body is fueled by breaking a chemical bond in ATP, the “currency of energy”. Did you know that you convert your body weight (or an estimated 50 kg) of ATP per day?!

Where does this ATP come from? It is synthesized by an incredibly sophisticated molecular machine, the ATP synthase, embedded in the inner membrane of our mitochondria. Energy from the oxidation of food results in protons being pumped across the membrane to create a proton gradient. The protons drive the rotation of a circular ring of proteins in the membrane that in turn move a central shaft. The shaft interacts sequentially with one of 3 catalytic sites within a hexamer, making ATP (little butterflies in the movie!). The ATP synthase rotates about 150 times/second

To visualize the rotation under a microscope, a very long fluorescent rod (actin filament) was chemically attached to the central shaft. Watch real movies (not animations!) of the enzyme spinning here: http://www.k2.phys.waseda.ac.jp/F1movies/F1long.htm

Notice the rotation is slower with longer rods. The rotor produces a torque of 40 pN nm (40 pico Newtons x nanometer), irrespective of the load. This would be the force you would need to rotate a 500 m long rod while standing at the bottom of a large swimming pool at the rate shown in the movie.

How did this amazing rotor evolve? The hexameric structure is related to DNA helicases that rotate along the DNA double helix, using ATP to unzip the two strands apart. The H+ motor has precedence in flagella motors that use proton gradients to drive rotation of long filaments, allowing bacteria to tumble through their surroundings. At some point, a H+ driven motor came together with a helicase like hexamer to create a rotor driving the hexamer in reverse, to synthesize ATP.

The 1997 Nobel prize in Chemistry was awarded to John Walker and Paul Boyer for solving the structure and cyclical mechanism of the ATP synthase, respectively. This amazing enzyme was also the subject of my own Ph.D. thesis, and my first love!

For #ScienceSunday curated by +Allison Sekuler and +Robby Bowles .
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Mark Whiting

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A great illustration of Fourier analysis!
 
The smooth motion of rotating circles can be used to build up any repeating curve even one as angular as a digital square wave. Each circle spins at a multiple of a fundamental frequency, and a method called Fourier analysis shows how to pick the radiuses of the circles to make the picture work. Decomposing signals like this lies at the heart of a lot of signal processing .
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Mark Whiting

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#ifihadglass I would make tools for the future of design without the constraints of current interfaces.
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Jeongbae Kong's profile photoAUGUST CRAFT's profile photoKyunghan Lee's profile photoMark Whiting's profile photo
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Yea?
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Mark Whiting
owner

Discussion  - 
 
Hey all. 

The mailing list they are using to manage the groups seems a little buggy. I noticed it looked like some people were not getting all of the messages. 

Hopefully this will be worked out before too long. 

Anyway, nice to meet you all. 
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Mark Whiting

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Chagall's colours are much much needed during Ottawa winter. Thank you for sharing (:
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