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Interesting new biological data for some of the OSDD malaria compounds. Firstly ZYH3-1 passes the hERG assay:

and a couple of compounds give very nice results in a late-stage gametocyte assay.

Explanation coming soon for non-malaria specialists, but wanted to flag the raw data supplied by collaborators.
In each graph the log of molar concentration of test compound is plotted against the effect of the compound on the hERG current, expressed as a percentage of the pre-compound signal. In this experimen...
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