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Mark Bothwell
Worked at University of Washington
Lived in LaConner, WA
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Mark Bothwell

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"NIH's spending capacity has dropped more than 20 percent over the past decade as the budget lines have failed to keep up with inflation or been reduced by policies like sequestration". 

The handwriting is on the wall -  the USA is on its way to becoming an also-ran in the world of medical research.
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Mark Bothwell

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Late blight is the nemesis of tomato growers. Fear breeds myths and misinformation.
Late blight is the nemesis of tomato growers, especially in the damp climate of the Pacific Northwest. Many sources of gardening advice include a lot of misinformation about managing late blight. For an authoritative source of good information, I recommend this pdf -Managing Late Blight.
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This pharmaceutical company is irresponsible beyond belief.  Based on results of a tiny Phase 2 clinical trial, Genervon has  petitioned the FDA to approve their drug for ALS under the Accelerated Approval program, which bypasses the normal requirement for a Phase 3 trial. In concert with this petition they have issued press releases indicating that the drugs effects are “very robust” and “dramatic.”   This media blitz has caused ALS patients, faced with near certain death, to put huge pressure on the FDA to approve the drug.

The thing is, the results of their Phase 2 trial are neither robust nor dramatic.  Their data (Table 3 in the following link) shows that the results just barely reach statistical significance, or fail to reach statistical significance, depending on which statistical test is applied. The company argues that this is remarkable because of the small number of patients enrolled in the trial. But the company has it exactly backwards - the smaller the number of individuals in a trial, the less the statistical "p" values should be trusted. 

http://www.genervon.com/genervon/about_pressreleases.php
The agency should balance “hope and hard science,” some patients say, but others urge caution.
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BTW, the problem with non-normality with the t-test is that the underlying distribution in the null hypothesis might not be normal. And in that case you have a problem with the test whether you have 10 observations or 1000 observations. That is a real problem but it's not limited to small samples.
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A desperate Netanyahu finally reveals his true colors, stating that he will never allow a Palestinian state to exist.  This is hardly any surprise, since his policy of rapidly building Israeli settlements on Palestinian land guarantees that no two-state solution could be possible. Nevertheless, this is the first time he has dropped the charade of publicly pretending he supports the creation of a Palestinian state.

I don't normally cite Faux news, but I did so in this case to prevent conservatives from claiming that I have misrepresented Bibi.
With his party facing a surprise defeat in looming parliamentary elections, Israeli Prime Minister Benjamin Netanyahu rallied thousands of supporters in Tel Aviv Sunday, warning of a real danger he could lose the premiership of a country he has governed for the past six years.
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Republican Governor Rick Scott's anti-science mafia prevents  Florida State officials from mentioning the words "climate change" or "global warming".  Another candidate for the Dick-Head of the Month Club.
State environmental officials ordered not to use the terms “climate change” or “global warming” in any government communications, emails, or reports.
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+Mark Bothwell​ I find absolutely nothing in this post to disagree with you on. You seem be taking a reasonable and rational approach to it. As we said before that's unusual so no debate from here. Thank you for the reply

My mistake, I thought you were saying something different than you were.
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You can take the elephant out of the circus but you can't take the circus out of the elephant.
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IE 11. I swear - I haven't had a web browser crash so frequently since the beta version of Mosaic, in 1993.
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+Mark Bothwell Hi!
We can Hangout and see how we can browse the Internet more efficiently.
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http://www.sanluisobispo.com/2015/03/17/3541385_chris-erskine-adieu-to-the-egg.html?rh=1

In lieu of flowers, donations to the James Beard Foundation would be appreciated.
The egg-white omelet, America's reigning symbol of bland dining and misguided nutritional advice, died on a recent Friday at Cedars-Sinai Medical Center in Los Angeles. It was 42.
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This is an official "press release" from a Congressional Committee.  If you have any remaining respect for Congress, this will kill it. 

I was taught to believe that one should treat mentally handicapped persons respectfully. This makes it difficult to criticize the Republican Congress.
 
This is an actual press release from your actual Congress. It can't get more infantile and pathetic. These people are making real laws. That's bad.

"Subcommittee on the Constitution and Civil Justice. The Subcommittee on the Constitution and Civil Justice shall have jurisdiction over the following subject matters: constitutional amendments, constitutional rights, Federal civil rights...."
Subcommittee on the Constitution and Civil Justice. The Subcommittee on the Constitution and Civil Justice shall have jurisdiction over the following subject matters: constitutional amendments, constitutional rights, Federal civil rights, claims against the United States, non-immigration private ...
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They call that a press release? that's got to be the most amateurish attempt to explain complex issues I've ever had a nightmare about. maybe they thought that it was cute, they were wrong. I had a hard time getting to the end, and I'm not sure my lunch going to stay down at this point. Thanks for bringing this to my attention. pardon me I'm going to go be sick. Level of discourse at the national level proves we have children running the government.
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I love this. An anti-virus program identifies its own core files as a virus. The result is like the ancient Egyption/Greek οὐροβόρος (snake eating its tail) with a similar level of ensuing dysfunction - i.e., your laptop is subsequently useful mainly as a door-stop.
Summary:Users were warned not to restart their PCs, in case they wouldn't boot up again.
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The problem with lying is that you have to remember your past lies.
Russian President Vladimir Putin has said he ordered officials to start work on taking control of Crimea weeks before a referendum which, the Kremlin has asserted until now, prompted the region's annexation from Ukraine. Russian state television channel Rossiya-1 aired a brief extract of an interview in which Putin said he had called an emergency meeting in February last year to discuss the overthrow of Ukrainian president Viktor Yanukovich hours...
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Softcard (formerly known as ISIS) can no longer be used for making NFC payments on Windows Phones.  Google is really sticking it to Microsoft. This leaves Windows Phone owners without any way to use tap-to-pay. How appropriate that Softcard was formerly known by the acronym of a terrorist organization.
It was nice while it lasted, but Windows Phone is without a viable tap-and-pay option in the U.S., again.
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The chief function of the body is to carry the brain around.-Thomas Alva Edison
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