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Tsai Laboratory
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Tsai Laboratory

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The integrity of our genetic material is under constant attack from numerous endogenous and exogenous agents. The consequences of a defective DNA damage response are well studied in proliferating cells, especially with regards to the development of…
The integrity of our genetic material is under constant attack from numerous endogenous and exogenous agents. The consequences of a defective DNA damage response are well studied in proliferating cells, especially with regards to the development of cancer, yet its precise roles in the nervous system are relatively poorly understood. Here we attempt to provide a comprehensive …
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Tsai Laboratory

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We are on National Geographic: Drug Tweaks Epigenome to Erase Fear Memories

A hurricane, a car accident, a roadside bomb, a rape — extreme stress is more common than you might think, with an estimated 50 to 60 percent of Americans experiencing it at some point in their lives. About 8 percent … Continue reading →
A hurricane, a car accident, a roadside bomb, a rape — extreme stress is more common than you might think, with an estimated 50 to 60 percent of Americans experiencing it at some point in their lives. About 8 percent of that group will be diagnosed with post-traumatic stress disorder, or PTSD. They will have …
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Our lastest publication on the Boston Globe: Science in Mind

MIT researchers find a drug that helps erase traumatic memories in mice. For years, neuroscientist Li-Huei Tsai has been unraveling the brain circuits that underlie memory, searching for approaches that might be helpful in treating Alzheimer’s disease. In…
MIT researchers find a drug that helps erase traumatic memories in mice. For years, neuroscientist Li-Huei Tsai has been unraveling the brain circuits that underlie memory, searching for approaches that might be helpful in treating Alzheimer’s disease. In 2007, the Massachusetts Institute of Technology scientist identified an experimental drug that could restore lost memories in mice. Lately, …
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Shankha Maiti's profile photo
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Limiting a certain protein in the brain reverses Alzheimer’s symptoms in mice, report neuroscientists at MIT’s Picower Intitute for Learning and Memory. Researchers found that the overproduction of the protein known as p25 may be the culprit behind the…
Limiting a certain protein in the brain reverses Alzheimer’s symptoms in mice, report neuroscientists at MIT’s Picower Intitute for Learning and Memory. Researchers found that the overproduction of the protein known as p25 may be the culprit behind the sticky protein-fragment clusters that build up in the brains of Alzheimer’s patients. The work, which was …
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Tsai Laboratory

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Tsai Laboratory

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New breakthrough from our Lab: Erasing traumatic memories. Lead authors: Johannes Graff & Nadine Joseph. Senior author: Li-Huei Tsai

New study identifies drug that could improve treatment of posttraumatic stress disorder. Continue reading →
New study identifies drug that could improve treatment of posttraumatic stress disorder.
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Have them in circles
11 people
Anike Wilkens's profile photo
Shankha Maiti's profile photo
Contract Laboratory's profile photo
Najat Kessler's profile photo
Kimberly Goh's profile photo
Mohammad Nasrullah's profile photo
MIT Bio's profile photo
Andrés Bahá'í's profile photo
Cleatech's profile photo
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(617) 324-1658
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77 Massachusetts Avenue 46-4235 Cambridge, Ma 02139
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Our primary goal is to elucidate the pathological mechanisms underlying neurological disorders affecting learning & memory. The major research areas include neuropsychiatric disorders, autism, and Alzheimer’s disease.
Introduction
Tsai Laboratory's primary goal is to elucidate the pathological mechanisms underlying neurological disorders affecting learning & memory. The major research areas include neuropsychiatric disorders, autism, and Alzheimer’s disease.