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Lev Osherovich
Attended UC San Francisco School of Medicine
Lives in San Francisco
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Lev Osherovich

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The Wall Street Journal on Venezuela's economic death spiral, the legacy of Hugo Chavez's redistributionist policies. Chavez died in 2013, leaving his hapless sidekick Nicolás Maduro holding the bag.

Inflation in this oil-rich country is expected to hit a world’s-worst 700% this year, according to the International Monetary Fund. The economy shrank by 10% last year and is expected to decline another 8% this year, according to the IMF, the worst performance in the world. And there is no end in sight.

Economists say Mr. Maduro’s government needs to reverse course on a decade of economic policies that dramatically reshaped the economy. The state took over hundreds of companies, instituted price controls and spent enormous amounts of public money, causing the country’s budget gap to swell to about 20% of annual economic output.

Despite the deepening crisis, there has been little sign of change from a government that blames the country’s woes on an “economic war” waged by enemies including private firms and the Obama administration. Calls requesting comment from various government ministries and agencies weren’t returned.

On Thursday, progovernment lawmakers said the food shortages were the fault of private companies hoarding products to try to destabilize Mr. Maduro. Later that night, the country’s Supreme Court gave Mr. Maduro special powers that allow him direct control over the budget and a freer hand in intervening in private companies. Opposition lawmakers said both moves were aimed at preventing them from trying to limit government intervention in the economy.


In Venezuela, dying infants, chronic power outages and empty shelves mark the world’s worst-performing economy.
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Paywall :-(
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Alemany Farm, San Francisco, California


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I'd no idea there was a mini farm on Alemeny Blvd. However I do see the "ticky tacky" houses.
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I spotted this Volvo V60 Polestar in my neighborhood and did a double take-- the rear plate is the same as the one I saw a few weeks ago elsewhere in San Francisco, not the other one I saw in my neighborhood on Jan. 1. This means there are two of these unicorns in my neighborhood.

#volvolove
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Man that thing needs to be garaged! I love those wheels.
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Collections limit

I hit the limit on the number of Collections (it's a very small number ). WTF with this arbitrary limitation? After G+ destroyed Circles as a note management system by hiding it under too many layers, I adopted Collections for that purpose. This limit thing is a deal breaker.
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I put G+ in a blender. I no longer care.
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This New York Times Op-Ed piece by Lionel Shriver laments the failure of moderate libertarian-leaning political positions to gain traction.

The mainstream of neither the Democratic nor the Republican Party (insofar as it has a mainstream anymore) represents my views, which qualify as left-wing or right-wing only on the basis of “eeny meeny miny moe.” During the nine months a year I live in London, I’m regarded as an archconservative nut. When I fly home to the United States, I transform, mid-Atlantic, to a leftist radical — with the same opinions. That’s because most of my progressive social positions are taken as the norm in Britain by just about everybody.
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Gleaming the cubane

Derek Lowe has this appreciation of cubane, an esoteric but potentially useful substituent than can replace phenyl groups in many medicinal syntheses.

Overall, the cubane derivatives are slightly more lipophilic than the phenyls, which makes sense just by eyeballing them. Metabolically, the ring system appears very stable – those hindered tertiary carbons are not very reactive. Cubane itself (as mentioned above) is thermodynamically rather elevated, but it’s quite stable, because there are really no easy ways for the structure to rearrange and break down. That’s probably helping it out with the p450 enzymes as well.

Citing a recent proof of concept that swaps cubanes into common medicinal compounds (though to no better effect), Lowe challenges med chem jocks to give the cubane a spin..

http://blogs.sciencemag.org/pipeline/archives/2016/02/09/cubane-to-the-rescue
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+John Baez​
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The New York Times reports on expectations of a strange creature in Slovenia.

The olm has several attributes fitting a creature of mythology. It can live as long as a hundred years and survive without food for 10. It is blind, but hunts using its incredible sense of hearing and smell, and it can detect electric and magnetic fields. Female olms only reproduce once every six years and it takes them until the age of 15 to become sexually mature

A Brood of Olms sounds like a novelette from G.R.R. Martin's A Song of Ice and Fire. Or a cause of death for a medieval English king.
To see the olms in Postojna Cave, you’ll need to take an underground train. But you might be rewarded with a glimpse of their crystal clear eggs.
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Near Lola's Lookout, Placer County, California

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+Mari Christian that's me!
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Autoweek.nl and Autofans have blown the cover off the forthcoming Volvo V90 wagon. Carscoops, which collected the leaked photos, says:

Based on the new S90 sedan, the V90 adopts a similar rear end styling to Volvo’s Concept Estate model from the 2014 Geneva Motor Show, with distinctive ‘L’ shaped rear lights that extend to the car’s roof, along with a slanted rear window that give it a less boxy look than the V70 it essentially replaces.

While I love new V90's design and am impressed by the power/efficiency of the new T6 and T8 drivetrains, I'm likely to be priced out of the V90. Pricing on the V90 has not been announced but I expect the base model to start at $55,000 USD with nicer trims selling north of $60,000.

As it happens, I am thinking about snapping up a new XC70 while I still can.

The XC70 (really just a raised and rubber-clad V70) is a lot of car for not much money. Advertised prices in my area are under $40,000 for the base T5 Drive-E FWD configuration and perhaps $45,000 for fancier trim AWD versions.

Car Geeps, what do you say: is the sleek and modern V90 worth waiting for over the XC70, the last of the classic boxy Volvos?

#volvolove
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Was handed this pack at +SFMagic​ draft. There seems to be some mimicry going on.
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Taken standing precariously on a steep hill in San Francisco.
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A jaunty but alarmingly Trump-like hut.
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Close enough to Donner Pass to get a feeling for what it was like. Feeling hungry?
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Lev's Collections
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In his circles
547 people
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549 people
Kevin Hedebrandt's profile photo
Hayley DeLugach's profile photo
Yeah Chemistry's profile photo
Jarvis Yu's profile photo
Bharath Kumar's profile photo
iOrganic-Zation's profile photo
Psylvia Gurk's profile photo
Nguyen Hoang Lan's profile photo
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Occupation
Molecular biologist
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Volvo enthusiast
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San Francisco
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Specializing in the general
Introduction
I use Google Plus for social interaction, news reading and note management.
Education
  • UC San Francisco School of Medicine
    Biochemistry
    Ph.D.
  • University of California, Berkeley
    Genetics
    B.A.
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Male
A delightful neighborhood cafe across from my hotel. A local clientele, a fun relaxed atmosphere and a menu of standard but excellently prepared French makes this place a treat to visit.
Public - a week ago
reviewed a week ago
Tiny, casual wine bar with limited but tasty menu. Chicken salad and the croque Napoleon were very satisfying. Service is excellent.
Public - 2 weeks ago
reviewed 2 weeks ago
Third time there and, alas, enjoying it less with every visit. The place remains extremely popular (I.e. crowded) but the nigiri seemed small, bland and uninspired. Other dishes were disappointing. For example, the okonomiyaki was slathered in spicy mayo and bonito flakes, making it too salty and spicy to enjoy. Considering the premium price, I expect higher quality and attention to detail. Unlikely to go again.
Public - 3 weeks ago
reviewed 3 weeks ago
An unassuming and laid-back Cantonese eatery that accommodates overflow from the overly popular Koi Palace, which is how we ended up there. Somewhat shabby interior but the staff were friendly and welcomed our kids. Good dim sum standards, bordering on excellent, plus a selection of unfamiliar and thus probably more authentically Chinese dishes. We enjoyed the lobster noodles and roasted squab. Would go back.
Public - 3 weeks ago
reviewed 3 weeks ago
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Dropped in for the Dine Out special, which highlights Miku's signature style including the torch-roastes salmon nigiri. Every item in the prix fixe menu stood out for fresh and bright flavors and beautiful plating. I agree with other reviewers -- superb upscale sushi.
Public - 3 weeks ago
reviewed 3 weeks ago
My favorite gaming shop on the Peninsula. I've gone there for Magic the Gathering events here for many years and have always enjoyed myself. Friendly staff, interesting and eclectic crowd of regular players. Everything a game shop should be.
Public - 3 weeks ago
reviewed 3 weeks ago
My regular. The best espresso in SF.
Public - 2 months ago
reviewed 2 months ago