Cherry-picking with organophosphates
A new review of organophosphate herbicide carcinogenicity published in The Lancet
by International Agency for Cancer Research, a World Health Organization research unit, makes a totally shocking claim that glyphosate (Roundup) is a dangerous Group 2A carcinogen.
This contradicts nearly everything we have previously learned about glyphosate, and is no doubt good news for Monsanto haters.
Alarmingly, glyphosate (Group 2A --"probably carcinogenic to humans") is ranked as more dangerous than tetrachlorvinphos and parathion (Group 2B -- "possibly carcinogenic to humans"). The latter compounds are banned or restricted in EU and US due to animal and human toxicity. Yet the actual evidence against glyphosate, summarized in the paper extract below, is weak and inconsistent. The 2A classification for glyphosate seems out of the blue. Glyphosate is a broad-spectrum herbicide, currently with the highest production volumes of all herbicides. It is used in more than 750 different products for agriculture, forestry, urban, and home applications. Its use has increased sharply with the development of genetically modified glyphosate-resistant crop varieties. Glyphosate has been detected in air during spraying, in water, and in food.There was limited evidence in humans for the carcinogenicity of glyphosate. Case-control studies of occupational exposure in the USA,14 Canada,6 and Sweden7 reported increased risks for non-Hodgkin lymphoma that persisted after adjustment for other pesticides. The AHS cohort did not show a significantly increased risk of non-Hodgkin lymphoma.In male CD-1 mice, glyphosate induced a positive trend in the incidence of a rare tumour, renal tubule carcinoma. A second study reported a positive trend for haemangiosarcoma in male mice.15 Glyphosate increased pancreatic islet-cell adenoma in male rats in two studies. A glyphosate formulation promoted skin tumours in an initiation-promotion study in mice.Glyphosate has been detected in the blood and urine of agricultural workers, indicating absorption. Soil microbes degrade glyphosate to aminomethylphosphoric acid (AMPA). Blood AMPA detection after poisonings suggests intestinal microbial metabolism in humans.Glyphosate and glyphosate formulations induced DNA and chromosomal damage in mammals, and in human and animal cells in vitro. One study reported increases in blood markers of chromosomal damage (micronuclei) in residents of several communities after spraying of glyphosate formulations.16 Bacterial mutagenesis tests were negative.Glyphosate, glyphosate formulations, and AMPA induced oxidative stress in rodents and in vitro. The Working Group classified glyphosate as “probably carcinogenic to humans” (Group 2A).
Plant science Geeps, what is going on here?+Mary Mangan