"Cancer is a genetic disease. There have been many theoretical models about the genesis of cancer that have been difficult to test experimentally. Single cell genome sequencing is the ultimate experiment. We propose to characterize the copy number and single nucleotide variations of one hundred individual cells from cancer tissues, from which we will be able to extract information regarding how genetic variations occur in real time in a solid tumor. We also plan to simultaneously determine the genome and the transcriptome of the same cell using the techniques described above. The implication of the proposed research on dynamics of the genome goes beyond cancer research and may have other broad implications to biology and medicine"
Hopefully this will lead to population-scale, longitudinal data that will allow us to detect the early, pre-symptomatic stages of disease---transforming medicine into a more predictive, rather than reactionary, process.
How fast will the transition to highly-distributed energy generation & storage be? If the Tesla+SolarCity collaboration is any indication, it will be quicker than most people expect---and utilities will need to figure out how to adapt.