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Ian Bosdet
Works at BC Cancer Agency
Attended University of British Columbia
Lived in Vancouver, B.C.
19,819 followers|1,316,152 views
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Ian Bosdet

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Rainbow Fountain, Van Dusen Gardens, Vancouver 
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Ian Bosdet

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Nihilistic password security questions 
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These two snoRNAs (snoRNA = small nucleolar RNA) are recurrently deleted in 10-40% of cancers. They are negative regulators of KRAS and their loss seems to make mutated KRAS, which is a bad feature of a tumour, even worse.

While this doesn't have obvious predictive value (i.e. there aren't therapies targeted KRAS, despite decades of work) the loss of these two RNAs provides some prognostic information. And perhaps finding molecules that target KRAS will help with design of future drugs.
Paul Khavari and colleagues analyze tumor genomes to identify snoRNAs showing frequent copy number loss of adjacently encoded snoRNAs SNORD50A and SNORD50B. These snoRNAs directly bound K-Ras and their loss leads to increased activity of both wild-type and oncogenic K-Ras and is associated with reduced survival.
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Fair and balanced reporting on the world around us
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Yeah, I meant that hopefully it won't go full Fox News. 
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The sun comes up and I have a chance to be kind to anyone who crosses my path because I can. I make that choice for myself and nobody has to tell me to do it. I am right with myself. I try my best to do my best, and if I fail, I try again tomorrow.
If there's no afterlife or reason for the universe, how do you make your life matter? Warning: the last answer may break your heart.
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SALAM PERTEMANAN,
MANUSIA MENENTUKAN SIKAP DAN PILIHAN 

TETAPI JANGAN LUPA,............................................................!

HIDUP INI MUNGKIN BAGAIKAN LINGKARAN,...................
HIDUP INI MUNGKIN BAGAIKAN SEGI TIGA,........................
HIDUP INI MUNGKIN BAGAIKAN SEGI EMPAT,................
HIDUP INI MUNGKIN BAGAIKAN ANAK PANAH,..............
HIDUP INI MUNGKIN BAGAIKAN KERTAS PUTIH,.........................

DAN ATAU HIDUP INI MUNGKIN,...............................................................

MANUSIA MENENTUKAN SIKAP DAN PILIHAN

MARI BERKARYA DI PLANET BUMI INI
                                                         
                                                         DIPOSKAN OLEH : 
                                                         KOMUNITAS ADAM MANUSIA HAWA
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The untenability of faitheism

Faith Versus Fact is unquestionably partisan, but its tone is matter-of-fact, and the offense that its targets will surely take will come from the force of his arguments rather than any ridicule or cheap shots.

Steven Pinker reviews +Jerry Coyne's new book Faith vs. Fact in the August issue of _Current Biology).
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Ian Bosdet

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Looking for a dietitian in Canada? +diana chard has you covered.
Last week after I wrote about the issue of dietitians sniping at each other I had a reader ask me how to find a “good” dietitian. That’s a bit of a tricky one but I’ll try m…
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He totally deserves this.
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It's a homophone (and a clever double entendre).  Because he's angry all the time.
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I should start practicing this now, but some days I think it may already be too late.
TACOMA, WA—Remarking upon the enormous caution she now takes before saying or doing anything in the presence of a loved one, local mother Sharon Powell, 64, told reporters Tuesday she knows any wrong move she makes could be interpreted by her family as a telltale sign of dementia.
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Hi
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47c/lb is a good price for premium boneless
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Wow! That's a low price!
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A wonderfully existential journey of a plastic bag, narrated by Werner Herzog. 
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Wow, great moves, keep it up!
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Quietly, without anyone really noticing, the entire Canadian blue-water navy has sunk.  It's now less-capable than those of Indonesia and Bangladesh, both of whom are long-time recipients of aid from Canada.
A maritime nation has let its naval fleet fall apart. Here’s how a once-proud force fell into such an embarrassing state of disrepair
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Wow, that's sad.
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People
In his circles
852 people
Have him in circles
19,819 people
Lila D's profile photo
Anders Lemke's profile photo
Edna Thackeray's profile photo
Rickey Visinski's profile photo
Clair McCowlen's profile photo
Simon Masters's profile photo
Tudor Lewis's profile photo
Ken “KDO” Orlich's profile photo
aameen alamdi's profile photo
Work
Occupation
Molecular Geneticist
Employment
  • BC Cancer Agency
    Clinical Molecular Geneticist, present
  • University of British Columbia
    Clinical Assistant Professor, present
  • Children's and Women's Health Centre of BC
    Fellow, 2012 - 2014
Places
Map of the places this user has livedMap of the places this user has livedMap of the places this user has lived
Previously
Vancouver, B.C.
Story
Tagline
Molecular Geneticist
Introduction
I'm a Molecular Geneticist specializing in cancer genetics.  My primary area of interest is applications of next-generation sequencing to clinical diagnostics.  I work mostly with non-small cell lung cancers and hereditary breast and ovarian cancer but our lab does a little bit (or a lot) of everything.
Bragging rights
I'm wild-type at many loci
Collections Ian is following
Education
  • University of British Columbia
    PhD, Genetics
Basic Information
Gender
Male
Relationship
Married