A problem ? No.
Serious work requires focus, so the temporary isolation is needed to reduce distraction (sorry, open space concept promoters).
Remote work only helps in that regard (proper remote worker's habits and ethic go without saying)
And it does not preclude remote meetings (hangouts, teleconferences...) - we do those, anyway, to compensate for the all-too-frequent "office geo-diversity".
Remote work with scheduled time in the office (even a regional/local one) works best since that office time is dedicated to the interaction with our colleagues. We may, actually, get more communication (the real kind) done in those few hours than in weeks of "water cooler chats".