Researchers have succeeded in reconstructing the neuronal networks that interconnect the elementary units of sensory cortex – cortical columns.
A key challenge in neuroscience research is identifying organizational principles of how the brain integrates sensory information from its environment to generate behavior. One of the major determinants of these principles is the structural organization of the highly complex, interconnected networks of neurons in the brain. Researchers have now developed novel techniques to reconstruct anatomically-realistic 3D models of such neuronal networks in the rodent brain. The resultant model has provided unprecedented insight how neurons within and across the elementary functional units of the sensory cortex – cortical columns – are interconnected. Read more: bit.ly/1EgOMry
Pictured:: Detail of 3D reconstruction of individual cortical neurons in rats.
Publication: Beyond Columnar Organization: Cell Type- and Target Layer-Specific Principles of Horizontal Axon Projection Patterns in Rat Vibrissal Cortex. Cerebral Cortex, 2015. doi: 10.1093/cercor/bhv053
Image credit: Max Planck Florida Institute for Neuroscience