London’s streets are a mess. Roads bend sharply, end abruptly, and meet each other at unlikely angles. Intuitively, you might think that the cells of our brain are arranged in a similarly haphazard pattern, forming connections in random places and angles. But a new study suggests that our mental circuitry is more like Manhattan’s organised grid than London’s chaotic tangle.

It consists of sheets of fibres that intersect at right angles, with no diagonals anywhere to be seen.Van Wedeen from Massachusetts General Hospital, who led the study, says that his results came as a complete shock. “I was expecting it to be a pure mess,” he says. Instead, he found a regular criss-cross pattern like the interlocking fibres of a piece of cloth.
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