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Creative Biogene
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Stable cell line, particles, cDNA, miRNA
Stable cell line, particles, cDNA, miRNA

251 followers
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Human hepatitis A virus cellular receptor 2 (HAVCR2) is the next promising target for cancer immunotherapy. HAVCR2 is also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2. It is encoded by HAVCR2 gene in human. Accumulating studies support the value of HAVCR2 as a target for cancer immunotherapy.
http://www.creative-biogene.com/support/HAVCR2-As-A-Promising-Target-For-Cancer-Immunotherapy

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Immune checkpoints are proteins which can turn up or turn down signals in the immune system. Inhibitors of immune-checkpoint proteins have been considered as new targets for cancer immunotherapies. To accelerate research progress of immune-checkpoint proteins, we have developed stable cell lines expressing the most popular immune checkpoints. http://www.creative-biogene.com/Product/Gene-Overexpression-Stable-Cell-Lines-Others.html

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Creative Biogene offers a variety of Direct PCR Kits for your research. Our Direct PCR Kits can save time from preparing purified DNA sample, and enable researchers to easily and directly do PCR reactions from various samples including blood, animal tissues, plant tissues and microorganisms etc. http://www.creative-biogene.com/Product/Direct-PCR-Kits.html
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With years of development and advanced electrochemical technique, Creative Biogene can design and synthesis user-specified DNA sequences on sized semiconductor chips: 12K (delivers 12,000 different oligos per chip) or 90K (90,000 different oligos per chip). Creative Biogene has years of professional and abundant experience that can help customers design and synthesis oligo pools to meet your downstream needs. Creative Biogene has confidence in providing you with the most affordable and high-quality service to ensure your satisfaction in a timely and professional manner.
http://www.creative-biogene.com/Services/Oligo-Pools.html

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Tn5 is utilized in genome sequencing for fragmentation of the DNA, in the technique called ATAC-seq. A great advancement in library preparation was the introduction of a hyperactive variant of the Tn5 transposase that mediates the fragmentation of double-stranded DNA and ligates synthetic oligonucleotides at both ends in a 5-min reaction. Creative Biogene offers 10% off for robust Tn5 transposase. Inquiry Now! http://www.creative-biogene.com/Product/Tn5-Transposase.html

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Microbe genome editing in pharmaceutical applications. Creative Biogene possesses two mature microbe genome editing platforms, traditional recombineering system and CRISPR/Cas 9 system, and can provide you microbe genome editing service to meet your pharmaceutical applications. You can select the following categories to best match your needs.
Bioactive Compounds
Probiotics
Biomedical Materials
http://www.creative-biogene.com/services/pharmaceutical-applications.html

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Microbe genome editing service to meet your needs of industrial application. Microorganisms, due to their ability to produce a variety of substances through a complex series of biochemical reactions, can be used to produce desired industrial products including biomaterials, biosensors and biocatalysts. Traditional recombineering system and CRISPR/Cas 9 system, can help you create new enzymes and pathways or modify the existing pathways to produce or increase the yield of desired products. http://www.creative-biogene.com/services/industrial-applications.html
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Creative Biogene is able to provide the following cardiac safety assay services to better predict the proarrhythmic liability of your test compounds:
Automated electrophysiology screening against multiple cardiac screen panels, including hERG, NaV1.5, CaV1.2, Kir2.1, KV1.5 etc.
Cardiac safety screen using iPSCs-derived cardiomyocytes.
Cardiac action potential assays of Purkinje fibers and papillary muscle.
Cardiac pharmacological study using acute isolated cardiomyocytes (from rabbit, Guinea pig or rats). http://www.creative-biogene.com/services/cardiac-safety-assay-services.html

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The overexpression of proteins is critical for many applications, including studying the function of the gene, screening activitors or inhibitors of the gene and other assay studies. At Creative Biogene, we have developed a large number of GPCR stable cell lines, Ion channel stable cell lines and Reporter stable cell lines. Besides GPCR, Ion channel and reporter cell lines, scientists at Creative Biogene have also investigated and generated recombinant stable cell lines expressing other popular gene targets such as immune checkpoints, Toll-like receptors (TLRs), Cas9, PDEs etc. http://www.biocart.org/Product/Gene-Overexpression-Stable-Cell-Lines-Others.html

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The immunoglobulin superfamily (IgSF) is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins, also known as antibodies. They all possess a domain known as an immunoglobulin domain or fold, which is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, consisting of about 125 amino acids. Members of the IgSF include cell surface antigen receptors, co-receptors and co-stimulatory molecules of the immune system, molecules involved in antigen presentation to lymphocytes, cell adhesion molecules, certain cytokine receptors and intracellular muscle proteins. http://www.creative-biogene.com/support/immunoglobulin-superfamily
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