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Creative Diagnostics
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a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components and critical assay reagents
a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components and critical assay reagents

242 followers
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Angiogenesis Signaling Pathway - Creative Diagnostics
Angiogenesis plays a central role in tumor growth and progression, and its implications have been extensively investigated and described in the literature for various cancers. Learn more: https://www.creative-diagnostics.com/angiogenesis-signaling-pathway.htm
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ROS1 Signaling Pathway - Creative Diagnostics
The c-ros oncogene 1 (ROS1) is a receptor tyrosine kinase with structural similarity to anaplastic lymphoma kinase (ALK) protein. It was discovered in the 1980s as the oncogene product of the chicken sarcoma RNA UR2 (University of Rochester) tumor virus. The receptor is expressed during development, but little is expressed in adults and its physiological function is unknown. Learn more: https://www.creative-diagnostics.com/ros1-signaling-pathway.htm
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Diabetes Signaling Pathway - Creative Diagnostics
Diabetes is a metabolic disease which affects not only the glucose metabolism but also lipid and protein metabolism. It encompasses two major types, including types 1 and 2 diabetes. Type I diabetes (T1D) is characterized by destruction of the β-cells of the pancreas and insulin is not produced, whereas type II diabetes (T2D) is characterized by a progressive impairment of insulin secretion and relative decreased sensitivity of target tissues to the action of this hormone. Learn more: https://www.creative-diagnostics.com/diabetes-signaling-pathway.htm
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Obese Signaling Pathway - Creative Diagnostics
Obesity means a person who's very overweight, at least 20% higher than it should be. It's a common problem in the US and worldwide. According to National Health and Nutrition Examination Survey (NHANES) data, it's estimated to affect around 30% adults and around 20% children aged 10 to 11. Learn more: https://www.creative-diagnostics.com/obese-signaling-pathway.htm
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Epigenetics Pathway - Creative Diagnostics
Epigenetics is the study of heritable nonencoded genetic changes that turn genes on or off. Examples include activating changes such as histone acetylation and DNA demethylation, repressive changes like DNA methylation and histone modifications induced by noncoding RNAs, such as microRNA and long noncoding RNA (lncRNA). Epigenetic modifications can modulate gene expression and/or alter cellular signaling pathways, which may affect individual susceptibility to various diseases. For example, epigenetic changes have been associated with the development of fibrosis in pulmonary fibrosis and liver disease. Learn more: https://www.creative-diagnostics.com/epigenetics.htm
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ALK Pathway - Creative Diagnostics
Anaplastic lymphoma kinase (ALK) is an enzyme that is encoded by the ALK gene in humans. Discovered in 1994, it was first identified as a receptor tyrosine kinase in a chromosomal translocation associated with some anaplastic large cell lymphomas(ALCL), where ALK takes its name. ALK was described as a fusion partner, and almost 70~80% of ALK-positive ALCL express the NPM–ALK which is an amino-terminal fusion derived from the nucleophosmin (NPM) protein. Learn more: https://www.creative-diagnostics.com/alk-pathway.htm
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Calcium Signaling Pathway - Creative Diagnostics
Calcium (Ca2+) serves as a ubiquitous second messenger in all eukaryotes. For an ever-increasing number of biological processes, it has been found that temporally and spatially defined changes of Ca2+ concentration in the cytoplasm or in defined organelles occur at one point or another. The importance of Ca2+ signaling pathway for the implementation of the information provided by Ca2+ has been increasingly appreciated, and several distinct families of Ca2+ sensing proteins have been identified and characterized. Learn more: https://www.creative-diagnostics.com/calcium-signaling-pathway.htm
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Tumor Immunology Pathway - Creative Diagnostics
Tumor immunology refers to the relationship between immune function and tumor cells, which is crucial for our understanding of the mechanisms of both tumor rejection and tumor progression. The immunological mechanisms involved in cancer growth are highly complex, including tissue-resident and blood-derived cells. Learn more: https://www.creative-diagnostics.com/tumor-immunology-pathway.htm
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Perforin/Granzyme Apoptosis Pathway - Creative Diagnostics
Perforin/granzyme apoptosis pathway is the primary signaling pathway used by cytotoxic lymphocytes to eliminate virus-infected and/or transformed cells. Studies in gene-disrupted mice indicate that perforin, in combination with granzyme, could induce apoptosis. It is vital for cytotoxic effector function and has an indispensable, but an undefined role in granzyme-mediated apoptosis. Learn more: https://www.creative-diagnostics.com/perforin-granzyme-apoptosis-pathway.htm
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Parkinson’s Disease Pathway - Creative Diagnostics
Parkinson’s disease (PD) is a devastating disorder of the nervous system. It is typically characterized by motor deficits that are closely associated with progressive degeneration and loss of dopaminergic neurons in the substantia nigra and pars compacta, as well as subsequent reduction of dopamine levels in striatum. Learn more: https://www.creative-diagnostics.com/parkinson-s-disease-pathway.htm
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