Window > Preferences > Java > Appearance -> Abbbrevkate package names
and the user is good to go without having to see a video (even it this one is short and clear). I know some people love to see videos, so that's good for them, but I prefer information that can be read at a glance, searched on Internet, etc.
Thanks for the information anyway. Our own package names were becoming too long and I didn't want to increase overly the width of the navigation tab.
#ldp #linkeddata #w3c
This discovery paves the way for a purely chemical method for the synthesis of genes. It has been demonstrated that human cells are still able to read through strands of DNA correctly despite being stitched together with a man made linker not found in nature. The artificially linked DNA was made by attaching oligonucleotides (oligonucleotides are short, single-stranded DNA or RNA) using click chemistry. Click chemistry is designed to mimic nature which allows it to generate substances quickly and reliably by joining small units together.
The click technique has high efficacy and demonstrates several advantages to popular alternative approaches. The technique involves assembling DNA strands in the lab using a combination of DNA synthesis, PCR amplification and enymatic ligation.
“As chemists we always sought to synthesise long strands of DNA but have been limited by our assumption that the phosphodiester bond is necessary for DNA to function in cells," says Dr Tavassoli, lead of the study. The DNA back bone is comprised of pentose sugars and phosphate groups that stitch the nucleotides together using phosphodiester bonds. The backbone acts as a scaffold for the four bases of the genetic code.
Where click DNA can set itself apart is in the fact that it does not need the phosphodiester backbone of the DNA at the site of DNA ligation. The click approach has a rapid and efficient method of stitching together modified DNA strands using the copper-catalsed alkyne-azide cycloaddition reaction.
“This is important because it shows that we don't have to stick to the phosphodiester backbone of the DNA at the site of DNA ligation," Dr Tavassoli explains. "This suggests that we can replace the enzymatic methods for DNA assembly and DNA ligation with highly efficient chemical reactions."
"This is a mind blowing advance that demonstrates chemistry's power to manipulate nature's nature," comments Nobel laureate Barry Sharpless at the Scripps Research Institute, US, who first described the click chemistry process. "I only dreamed I'd get to see click chemistry do this in my lifetime. It is a marvellous achievement."
Read more here: http://goo.gl/OysY8K
- Base22Software Solution Architect, Partner, and CTO, 2007 - present
I am a co-founder of Base22, an Enterprise Web Architect, entrepreneur, I.T. innovator, and writer.
I help people leverage and get the most our of their investments in enterprise-class platforms such as IBM WebSphere Portal, IBM Web Content Manager, and IBM Connections. I bring proven principles, patterns, experience, and accelerators that have helped titans of global commerce evolve and grow. I can help large organizations succeed with complex challenges and evolve their information enterprise. My goal is to provide real, honest-to-goodness value to our customers and leave them all proudly saying, "Now THAT is what this technology was made to do!"
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