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Vaccinating Boys Against HPV Proves Cost-Effective
Vaccinating adolescent boys against the human papillomavirus (HPV) may be cost-effective in the prevention of oropharyngeal cancer, according to the results of a study published in Cancer. Image © Sherry Yates Young / Shutterstock.com

http://www.cancernetwork.com/head-neck-cancer/vaccinating-boys-against-hpv-proves-cost-effective?cid=G
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Small Benefit of Follow-Up Imaging in DLBCL Comes With High Costs
The use of routine follow-up imaging with CT or PET/CT to monitor asymptomatic patients with diffuse large B-cell lymphoma (DLBCL) resulted in little survival benefit and substantial economic cost, according to the results of a recently published cost-effectiveness analysis.

Image © skyhawk x / Shutterstock.com

http://www.cancernetwork.com/hematologic-malignancies/small-benefit-follow-imaging-dlbcl-comes-high-costs?cid=G
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Lymph Node Staging in Localized Breast Cancer

Cancer Network: Dr. Dominici, could you describe what the current guidelines recommend for lymph node dissection in breast cancer patients?

Dr. Dominici: Certainly. For women with clinically node-negative breast cancers, the evaluation of the axillary nodes with a sentinel lymph node biopsy has really become the standard of care. Sentinel node evaluation continues to provide the necessary staging information and informs the clinical decision-making while sparing many women the morbidities of an axillary lymph node dissection. For women with clinically node-positive breast cancers, however, the axillary lymph node dissection remains the standard of care.

http://www.cancernetwork.com/podcasts/lymph-node-staging-localized-breast-cancer?cid=G
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Interesting podcast on improving quality of life with yoga!
 
It’s common for cancer patients to experience stress and anxiety during cancer treatment. One thing that can help ease those cancer treatment symptoms is sleep yoga. Also called yoga nidra, this type of yoga helps patients slow down their minds and relax, says Smitha Mallaiah, a mind/body intervention specialist in Integrative Medicine at The University of Texas MD Anderson Cancer Center.

Listen to this podcast to learn more about sleep yoga: http://bit.ly/1ES2tkK #yoga #sleepyoga #yoganidra #cancertreatment #cancer #cancersideeffects #stress #anxiety #endcancer
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Prevent #cancer!
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Fascinating!
 
Head and Neck Cancer: Building the Evidence Base for Precision Oncology http://1.usa.gov/1JeEYGU
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SBRT Offers Short-Term Improvements Over Surgery in Early-Stage NSCLC
Though surgery is the standard treatment for early-stage non–small-cell lung cancer (NSCLC), a new study suggests that stereotactic body radiotherapy (SBRT) offers lower immediate mortality and toxicity. Over the longer term, however, there is benefit with surgery over SBRT.

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http://www.cancernetwork.com/lung-cancer/sbrt-offers-short-term-improvements-over-surgery-early-stage-nsclc?cid=G
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Most Early Breast Cancer Patients Avoid Full Lymph Node Removal
Most women with early-stage breast cancer now have sentinel node biopsy (SNB) as opposed to axillary lymph node dissection (ALND), consistent with recommendations based on clinical trials, according to results of a study published in the Journal of the American College of Surgeons. This represents a major change in the clinical management of breast cancer. Image © Blamb / Shutterstock.com

http://www.cancernetwork.com/breast-cancer/most-early-breast-cancer-patients-avoid-full-lymph-node-removal?cid=G
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If the healthcare community is able to meet the National Colorectal Cancer Roundtable’s goal of increasing uptake of colorectal cancer screening in the United States to 80% by 2018, a new study estimates that 280,000 new cancer cases and 200,000 cancer deaths could be averted within 20 years.

According to a study published in the journal Cancer, only 58% of US adults aged 50 to 75 years received guideline-recommended colorectal screening in 2013. The National Colorectal Cancer Roundtable, a national coalition of public, private, and voluntary organizations, recently announced an effort to increase this rate of screening to 80%, a 22% increase, by 2018.

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http://www.cancernetwork.com/colorectal-cancer/increased-screening-may-decrease-incidence-mortality
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IGF2BP1 Gene Plays Big Role in Neuroblastoma

Expression of the IGF2BP1 gene was associated with more advanced tumors and decreased patient survival in a study of neuroblastoma, suggesting that this could be an oncogene with prognostic value.
In previous work, high expression of the IGF2BP1 protein has been shown to be associated with poor overall prognosis and tumor metastasis in a number of cancers. The protein also appears to sustain elevated MYC expression, and MYCN expression plays a role in neuroblastoma tumorigenesis and tumor type.

http://www.cancernetwork.com/brain-tumors/igf2bp1-gene-plays-big-role-neuroblastoma?cid=G
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Amonafide Regimen Not Superior to Standard Care in Secondary AML

Induction treatment for acute myeloid leukemia (AML) with amonafide L-malate plus cytarabine failed to improve the rate of complete response compared with treatment with daunorubicin plus cytarabine, according to the results of a study designed to test treatment with amonafide L-malate, a DNA intercalator and non–ATP-dependent topoisomerase II inhibitor that evades drug resistance mechanisms.

“On the basis of previous phase I and II clinical trial data and a mechanism of action including evasion of drug efflux, the induction regimen of [amonafide/cytarabine] held the promise of being superior to standard [daunorubicin/cytarabine] in patients with difficult-to-treat secondary AML,” wrote study researcher Richard M. Stone, MD, of Dana-Farber Cancer Institute, and colleagues in the Journal of Clinical Oncology. “Our study demonstrated that the doses of amonafide used in the experimental arm plus cytarabine did not produce a higher complete response rate than the use of standard therapy with [daunorubicin/cytarabine]. Moreover, the amonafide-containing regimen was more toxic than standard induction, making it less likely that inadequate doses of amonafide were used in this study.”

http://www.cancernetwork.com/leukemia-lymphoma/amonafide-regimen-not-superior-standard-care-secondary-aml?cid=G
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10 Ways Doctors and Patients Can Avoid Hating Each Other

Patients appreciate punctuality, but there are unexpected situations that can set you back. I always apologize for a wait. Please accept my apology graciously. However, if someone makes you wait an unacceptable period every time you have an appointment, I think you are foolish to stay with that provider. If you have no respect for your time, neither will he/she. Likewise, do not wander in 15 minutes late for your appointment and think that does not cause havoc for the rest of my day. And if you are not coming, please call and cancel.

http://www.cancernetwork.com/blog/10-ways-doctors-patients-can-avoid-hating-each-other?cid=G
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Cancer Network provides research and opinion on the screening, early detection, diagnosis, treatment, and prevention of cancers.
Introduction

Through a variety of clinical, educational, and practice management tools, Cancer Network is designed to meet the informational needs of today's busy cancer care specialist.

Offering an array of clinical content highlighting the latest research, updates from important medical meetings, CME opportunities, and access to the Cancer Management Handbook, Cancer Network is considered to be a leading source of information among the community of cancer care clinicians.