To go with the one about how 640k is enough RAM. Note -- the method is still very handy and valuable, and the paper a good piece of science. But the below is funny:
"One approach to high-throughput genotyping of SNPs is to type multiple polymorphisms one individual at a time with high-density oligonucleotide hybridization arrays (Wang et al. 1998). The capacity of the first commercially available array is limited to 1500 SNPs. It will be a problem to increase this number of SNPs as the simultaneous (multiplex) PCR amplification required will become increasingly laborious and difficult to control."http://www.ncbi.nlm.nih.gov/pmc/articles/PMC310828/
The latest Illumina human genotyping array (Omni5) has 4.3 million fixed and an additional 500,000 custom SNPs per array.