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Alice Williamson
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Alice Williamson

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Please vote!
 
Open Source Malaria have entered a competition and we need your help. The prize is money that will go straight into the project to fund our research. There's just one day left. If you have a couple of minutes to spare then please vote for us! https://thinkable.org/submission/2136
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Alice Williamson

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New Open Lab Course in Malaria Drug Discovery.
 
Undergrad lab course developed at +The University of Sydney  by +Alice Williamson where students do real research and share full lab books. (They even made a bunch of videos). Imagine what we might be able to achieve if lots more uni lab courses did this.
Last semester at Sydney Uni, Alice Williamson created a new lab course in what's known as the "Special Studies Program" in Chemistry - high achieving undergrads who are given the freedom to try something new and challenging. Alice, working with Adam Bridgeman and Peter Rutledge in the School of ...
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Write up of a recent meeting for the +Open Source Malaria project
 
Short write-up of my satellite session at #okcon that took place at #WHO on open approaches to drug discovery. Video and longer article coming. It was interesting and productive - we had 35 of the right people in the room and being constructive while disagreeing, including +Alice Williamson +Katrina Badiola +Patrick Thomson +George Papadatos Peter Murray-Rust 
New ways of developing affordable medicines were the subject of a meeting held recently at TDR. Experts from a variety of fields, including law, pharmaceutical development, ethics and national medical delivery, came together to explore how drug discovery can be done in an open and collaborative manner. Today, the internet can provide more access to data and introduce efficiencies in drug screening, discovery and development. However, policies an...
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Alice Williamson

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Hey everyone! If you are interested in learning about open notebook science, then sign up for the FREE class hosted by the #Scifund Challenge
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Minutes of OSDD Malaria Online Project Meeting Four (13th May 2013)
are now posted.
Please let us know if you'd like to get involved!
http://malaria.ourexperiment.org/osddmalaria_meeting_/7502/OSDD_Malaria_Online_Project_Meeting_Four_130513.html
Minutes of the Meeting: (AEW). Present: Matthew H Todd (MHT), Paul Willis MMV (PW), Alice E Williamson (AEW), Murray N Robertson (MNR), Althea Tsang (AT), Gaby (G), Greta Schmitt (GS), Peter Murray-Rust (PMR). Apologies: Matin Dean (MD), Patrick Thomson (PT). A) Actions arising from meeting on ...
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Alice Williamson

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Come along!
 
Next Open Online Meeting of the Open Source Drug Discovery for Malaria Project

When: Monday May 13th.
Times:
San Francisco 11 pm (Sunday 12th)
New York 2 am
London 7 am
Geneva 8 am
New Delhi 11:30 am
Sydney 4 pm
Where: http://webconf.ucc.usyd.edu.au/osddmalariamay132013/
Who: Anyone
Particularly who: med chemists and people with experience with using Github for science research.

Agenda:
1) Actions arising from meeting on Feb 26th: http://www.thesynapticleap.org/node/441
2) Consideration of new data from arylpyrrole series
3) Consideration of new data and action items from aminothienopyrimidine series: http://openwetware.org/wiki/OSDDMalaria:GSK_Amino-thienopyrimidine_Series#Current_Needs_of_This_Project
4) Construction of Top 10 for next round (if applicable)
5) AOB
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Alice Williamson

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Can you vote for OSM? Please do!
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Calling all medicinal chemists...can you help us to decide on a good synthetic route for the series four amides?
Blog Post here: http://malaria.ourexperiment.org/uri/44b
GitHub thread here: https://github.com/OpenSourceMalaria/OSM_To_Do_List/issues/101
Thanks a lot!

P.S...if you would like to sign up for GitHub, instructions are here: http://malaria.ourexperiment.org/uri/42b
The team want to synthesise some amides based on the data from the CRO and Pfizer on the series four triazolopyrazines. Some synthesis data on known compound MMV670652 was available from the CRO, however, so far no experimental data has been provided for the amides (example below and here).
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The team are trying to tie up the (or even better discover an amazing new representative) aminothienopyrimidine.

http://malaria.ourexperiment.org/the_osm_blog/7974/Choosing_the_final_aminothineopyrimidine_compounds_for_synthesis_and_evaluation.html
+Mike Robins has written an awesome new (and open) voting tool for members of the community to vote for favourite compounds:
http://115.146.93.123/quiz/
Please vote if you get chance and post any feedback here, on the comments to the blog or tweet us @O_S_M. Your feedback on the voting platform are also very welcome.
Cheers 
Team OSM
At the end of May, an open consultation was held to decide the next aminothienopyrimidines for synthesis as part of the OSM project. The team postulate that this round of synthesis might be the last for the aminothienopyrimidines (ATPs) and want to select the 'best' compounds to give a detailed ...
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Patentless open competitions and prizes (with an emphasis on drug discovery)
I recently read Future Perfect by Steven Johnson. The book articulates what is meant by a person being a "Peer Progressive" - someone with a set of values based on the power of distributed networks...
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Fancy a medchemathon this weekend? Can you help us.....yes you can!
 
Are you a medicinal chemist? Can you help us to select our next round of compounds for synthesis? The OSDDMalaria team needs you!
A summary of the status of our aminothienopyrimidine series is posted here: http://malaria.ourexperiment.org/uri/39f
Vote for your favourite compounds or suggest new ones here.
Many Thanks
Team OSDDMalaria
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We made number 5 in this list of malaria innovations in the Guardian!
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Have her in circles
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Lucy Simpson (hello12)'s profile photo
Matthew Tarnowski's profile photo
Aura Jarquín (antropóloga política)'s profile photo
Tianyi Zheng's profile photo
Martin Okane's profile photo
Soo Jean Park's profile photo
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