Profile

Cover photo
Able Lawrence
Works at SGPGIMS
Attended SGPGIMS
Lives in Lucknow
177,401 followers|12,048,160 views
AboutPostsCollectionsPhotosYouTubeReviews

Stream

Able Lawrence

Shared publicly  - 
 
Asian openbill Anastomus oscitans 
A type of large stork found in India and south-east Asia with a peculiar open configuration of the bill. The bill is an adaptation for its specialized diet which is composed almost exclusively of water snails which they extract from the shells without breaking the shell using its bill and unique technique which other birds are not able exploit so efficiently. They are resident in most of the areas where they are found (with some seasonal movements) and frequent different types of wetlands where snails are found. In my area, I found them foraging on different parts of the wetland on different days. Here is a video of the openbill eating snail. http://www.arkive.org/asian-openbill/anastomus-oscitans/video-17d.html
If you like Birds and posts about Birds, check out my collection 
https://plus.google.com/collection/QSO9a
188
14
SN World's profile photoNasir Miyan's profile photokamaroway günther's profile photoOlexiy Kulchytskyiy's profile photo
14 comments
 
VERY NICE
Add a comment...

Able Lawrence

Shared publicly  - 
 
Brain folds follow the scaling laws of paper folding 
The brains of different animals look very different from each other to us but appear to follow the same scaling laws. When paper is folded, it follows certain scaling laws depending on the surface area and thickness. Folds increase with area and decrease with the thickness contrary to the earlier belief that folding was related to the number of neurons. #BrainEvolution   #Evolution   #Brain  
Knowing when to fold them
http://www.sciencemag.org/content/349/6243/31.full
Cortical folding scales universally with surface area and thickness, not number of neurons
http://www.sciencemag.org/content/349/6243/74
Simple physics of crumpling explains elaborate folding of mammalian brains
21
5
Romilda Imondi's profile photoAnastasia K's profile photo
Add a comment...

Able Lawrence

Shared publicly  - 
 
Asian Koel male Eudynamys scolopaceus 
A large cuckoo resident in India and south-east Asia, (also called common koel or western koel) they are sexually dimorphic with males all black except for red eyes and pale bill while the females are spotted with barring on tails. Both the males and the females sing (different calls) and the fledglings male the kaa..kaa call of the crow (in India). In India, koels are brood parasites of crows while they are known to use other species ranging from thrushes to shrikes. Unlike other cuckoo species, they are predominantly frugivorous with occasional intake of insects. They live in open forests ad well as human habitations with trees as they like to remain mostly hidden (like all cuckoos) from where their song can be heard mainly in the mornings during breeding season. #Birds   #birdphotography  
If you like Birds and Birding posts, check out the collection on Birds
https://plus.google.com/collection/QSO9a
379
29
Roman Anisimov's profile photoHariraj E's profile photoneel patel's profile photoghulam Shabbir's profile photo
19 comments
 
Beautiful - thanks for info
Add a comment...

Able Lawrence

Shared publicly  - 
 
Single celled predatory organism evolves a way to make a human-like eye 
We would think that only multicellular organisms can have complex organs like eyes but eyes have evolved independently several times in arthropods (compound eyes in insects) to the eyes of cephalopods (squids and octopusses). It was known that single celled dinoflagellates have an eye-like structure callled ocelloid and now detailed studies of its structure has solved the mystery. It is organized from pre-existing organelles like mitochondria and plastids to get the eye like structure. _Eye-like ocelloids are built from different endosymbiotically acquired components_
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14593.html
A single-celled marine plankton evolved a miniature version of a multi-cellular eye, possibly to help see its prey better, according to University of British Columbia (UBC) research published today in Nature.
21
3
Darth Minty's profile photoAnita Adam's profile photoTin Daddy's profile photo鍾英's profile photo
2 comments
 
Every single religious person should read this. Sadly, very few would understand
Add a comment...

Able Lawrence

Shared publicly  - 
 
Wire-tailed swallow Hirundo smithii
A smallish swallow which is widespread resident in tropical Asia and Africa. It has white undersides and rufous chestnut crown and forehead along with metallic blue on the rest of the upperparts. It key distinguishing feature is the elongated outer rectrices (tail feathers) that form the wire-tail which can either be difficult to see in flight or absent or short in juveniles. Although primary habitat is the grasslands near rivers, they also are found near canals and some of them even nesting inside the aqueducts. They also roost in small to very large mixed flocks on powerlines at dawn and dusk. During day they are mostly actively hunting insects on the wing. #Birds   #birdphotography  If you like to see and read about birds, check out my collection Birds https://plus.google.com/collection/QSO9a
497
72
Khalld Alsalleh Alsalleh's profile photoAamir Abdullah's profile photoAngelina Del Carmen Cabrera Villarreal's profile photofouad attar's profile photo
28 comments
 
Now that is interesting concept but it remind be of that marble which I took our water and it had so nice touch same colour combination.
Add a comment...

Able Lawrence

Shared publicly  - 
 
How does the Rose gets its scent
Among all the scents of the world, rose and jasmine are the most universally loved inspiring even the great Shakespeare. Now a research paper has deciphered the secret of the scent of the Rose. 
Interestingly it turns out that Rose plant produces geraniol and the derivatives using a pathway different from other plants. How is this useful. Most modern rose varieties have lost their scent in the race to breed them for visual appearance. Understanding the pathway can make it easier to regain the scents either through marker assisted breeding or through recombinant methods. 
Biosynthesis of monoterpene scent compounds in roses
The scent of roses (Rosa x hybrida) is composed of hundreds of volatile molecules. Monoterpenes represent up to 70% percent of the scent content in some cultivars, such as the Papa Meilland rose. Monoterpene biosynthesis in plants relies on plastid-localized terpene synthases. Combining transcriptomic and genetic approaches, we show that the Nudix hydrolase RhNUDX1, localized in the cytoplasm, is part of a pathway for the biosynthesis of free monoterpene alcohols that contribute to fragrance in roses. The RhNUDX1 protein shows geranyl diphosphate diphosphohydrolase activity in vitro and supports geraniol biosynthesis in planta
http://www.sciencemag.org/content/349/6243/81.full
The flowering of a new scent pathway in rose
http://www.sciencemag.org/content/349/6243/28.summary
232
29
Ethirajan M's profile photozia ur rahman khokhar's profile photoApril Theriot's profile photoWFCD CUBBY's profile photo
11 comments
 
Sweet aaart n great artist think she is ur dream girl
Add a comment...

Able Lawrence

Shared publicly  - 
 
What makes us human?
Comparison of human DNA with that of other organisms have informed us how similar we are and we have not managed to get a grip on the differences. Recently, scientists inserts bits of human sequences in mice to get modest increases in brain size and neuron number but there are more questions than answers. Now researchers are beginning to attack this problem by inserting more such gene sequences in mice and seeing the effects. It is still the beginning as some of the effects may arise only from the interactions of more than one loci. 
#evolution   #HumanEvolution   #BrainEvolution  
Researchers are adding human DNA to mice to pinpoint sequences that helped define our species.
29
4
鍾英's profile photomanoj kumar's profile photoMr.Lesley D. McCain's profile photoJulie Boudreau's profile photo
2 comments
 
Planet of the Mice.
Add a comment...

Able Lawrence

Shared publicly  - 
 
Antidepressants and Parkinsons disease drugs affect moral decisions 
Experimental study has discovered that drugs that modulate serotoninergic (citalopam and other antidepressant drugs of the SSRI class) and dopaminergic (L-Dopa and anti-Parkinson's drugs) influence moral judgement. While increasing serotonin effects enhance our hyper altruism (the aversion to harming others for profit), dopamine makes us more prone to harm others. Scientists conducted the experiment by rewarding people with money for giving electric shocks to themselves or others to establish an "exchange rate" for self harm or harming others. On average, people were more willing to harm themselves and averse to give shock to others, the phenomenon called "hyperaltruism". 
Dissociable Effects of Serotonin and Dopamine on the Valuation of Harm in Moral Decision Making
http://www.cell.com/current-biology/abstract/S0960-9822(15)00595-3
Serotonin and dopamine drugs may change willingness to inflict harm on self and others
17
15
Saida Evans's profile photoAble Lawrence's profile photoKnowledge for LIFE (Know4LIFE)'s profile photoEric Smalley's profile photo
5 comments
 
+Joan Laine saw it already, thanks! Absolutely no surprise to me and I was familiar with quite a bit of what's mentioned. 
Add a comment...

Able Lawrence

Shared publicly  - 
 
How the ordour receptor OR7D4 shaped the domestication of the pig 
Androstenone is a male hormone produced by pigs and the ability to perceive the smell is linked to OR7D4 receptor. Research has shown that different individuals with different alleles of the receptor perceive androstenone differently. Those with well functioning receptor perceive it as foul smelling while those with some versions feel it is sweet and others cannot sense it at all. People in Africa along with other ancestral populations like Neanderthals and Denisoans could perceive it while those living in Northern Eurasia where pig was domesticated couldn't perceive the smell. Perhaps domestication of the pig was made possible because of this mutation. 
Global Survey of Variation in a Human Olfactory Receptor Gene Reveals Signatures of Non-Neutral Evolutio
http://chemse.oxfordjournals.org/content/early/2015/06/13/chemse.bjv030.full.pdf
18
2
Anita Adam's profile photo鍾英's profile photo
Add a comment...

Able Lawrence

Shared publicly  - 
 
New mechanism for DNA repair discovered 
Structure of transcribed chromatin is a sensor of DNA damage 
Early detection and repair of damaged DNA is essential for cell functioning and survival. Although multiple cellular systems are involved in the repair of single-strand DNA breaks (SSBs), it remains unknown how SSBs present in the nontemplate strand (NT-SSBs) of DNA organized in chromatin are detected. The effect of NT-SSBs on transcription through chromatin by RNA polymerase II was studied. NT-SSBs localized in the promoter-proximal region of nucleosomal DNA and hidden in the nucleosome structure can induce a nearly quantitative arrest of RNA polymerase downstream of the break, whereas more promoter-distal SSBs moderately facilitate transcription. The location of the arrest sites on nucleosomal DNA suggests that formation of small intranucleosomal DNA loops causes the arrest. This mechanism likely involves relief of unconstrained DNA supercoiling accumulated during transcription through chromatin by NT-SSBs. These data suggest the existence of a novel chromatin-specific mechanism that allows the detection of NT-SSBs by the transcribing enzyme.
http://advances.sciencemag.org/content/1/6/e1500021
The DNA molecule is chemically unstable giving rise to DNA lesions of different nature. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed.
6
3
John Blossom's profile photoVincenzo Sicari's profile photoAntonio Ardito's profile photoChasity Leegaard's profile photo
2 comments
 
Hmm, aging control in the making?
Add a comment...

Able Lawrence

Shared publicly  - 
 
Understanding the role of trees in absorbing Carbon dioxide
We think that trees in the forest absorb the carbon in the atmosphere but it is not settled an issue as we might think. According to current wisdom of ecologists, well established ecosystems do not absorb or release carbon as the incorporation into plant material is balanced by decay and destruction. Why is this important. Three-fourths of the Carbon released by burning fossil fuels remains in the atmosphere and oceans contributing to global warming. The rest one-fourth that gets sequestered is called the missing Carbon. While recent studies have shown that the worlds forests are going through a growth spurt, the details are too uncertain for use in reliable climate models. More over this growth spurt wont last forever. Therefore scientists are tracking the growth of forests and their accumulation of biomass. They are using methods from old fashioned tape measures to carbon dioxide flux monitoring to satellite and aerial photography. #climatechange   #missingcarbon  
Researchers are racing to determine whether forests will continue to act as a brake on climate change by soaking up more carbon.
63
11
P Thompson (Fidalgo)'s profile photoMariecel Faburada's profile photoR Cl's profile photoAjai Mani Tripathi's profile photo
 
Trees are radioactive, this is where to bury it. Not in nevada, they use it up. these trees can use a trillion rads a month.
Add a comment...

Able Lawrence

Shared publicly  - 
 
Ballooning spiders can cross water barriers 
It has been known that the ballooning spiders can disperse large distances in wind, that too deliberately and water bodies were considered a barrier but recent experimental studies are showing otherwise. #Adaptation   #spiders  
Water is no barrier to flying arachnids’ dispersal.
31
6
Ирина Лапшина's profile photoOlexiy Kulchytskyiy's profile photoSheila Browne's profile photoKP Jayabhanu's profile photo
2 comments
 
Evolving.. 
Add a comment...
Able's Collections
People
Have him in circles
177,401 people
Joel Needham's profile photo
Chris Brignola's profile photo
John Richardson's profile photo
beauty 4 u's profile photo
Kevin Nguyen's profile photo
Chris Mondragon's profile photo
Timothy Day's profile photo
Devon McKinney's profile photo
Henrry Gonzalez's profile photo
Work
Occupation
Doctor; Rheumatology and Clinical Immunology
Skills
Rheumatology, Statistics
Employment
  • SGPGIMS
    Additional Professor, Clinical Immunology, 2011 - present
  • SGPGIMS
    Associate Professor, Clinical Immunology, 2008 - 2011
  • SGPGIMS
    Assistant Professor, Clinical Immunology, 2004 - 2008
  • Amrita Institute of Medical Sciences
    Assistant Professor, Rheumatology and Immunology, 2004 - 2004
  • SGPGIMS
    Specialist Registrar, Clinical Immunology, 2000 - 2003
Places
Map of the places this user has livedMap of the places this user has livedMap of the places this user has lived
Currently
Lucknow
Previously
Kerala - Kozhikode - Chandigarh - Kochi - Thiruvananthapuram
Story
Tagline
Physician, Rheumatologist and Immunologist, Closet Geek, Mad about Birds, Photography,technology, statistics, physics, and food. Wanna be philosopher.
Introduction
Additional Professor, Department of Clinical Immunology, SGPGIMS, Lucknow
Bragging rights
Volunteered for Live vaccine Phase I trial
Education
  • SGPGIMS
    DM Clinical Immunology, 2001 - 2003
  • PGIMER
    MD Internal Medicine, 1997 - 2000
  • Kozhikode Medical College
    MBBS, 1989 - 1995
  • Sainik School Kazhakootam SSKZM
    1982 - 1989
  • St Mary's High School
    1977 - 1982
Basic Information
Gender
Male
Other names
A L Thoppil
Apps with Google+ Sign-in
  • Babbel
Tasty but very spicy. Those who like excessively spicy Indian food would love it though.
Public - 3 weeks ago
reviewed 3 weeks ago
Excellent dinner buffet with good variety. Almost everything is good with a balance of flavors, not overly spicy like other places (Just right). Desserts also good. Avoid over-eating starters. Best eatery in Lucknow at this time
Public - 3 weeks ago
reviewed 3 weeks ago
It was worth every penny of it. For best value, book online in advance and reach on time. Leave somewhat early, even the London tube can breakdown. (It happened twice during my four days in London).
Public - 3 weeks ago
reviewed 3 weeks ago
Bought two items from their online store. Total fraud. Over several weeks one item still remains pending. The other was totally damaged and they dont have a return policy other than trying to force customers to accept them. They dont even email an order confirmation Their call center does not work. Here is a link to a facebook page of aggrieved customers. Buy at your peril
Public - 11 months ago
reviewed 11 months ago
29 reviews
Map
Map
Map
Within walking distance of Metro and the Business design center. Breakfast buffet was good. Wifi didnt work
Public - 3 weeks ago
reviewed 3 weeks ago
We had veal schnitzels and Pig in a blanket. Both awesome.
Public - 4 weeks ago
reviewed 4 weeks ago